December 10, 2025

Three-hit model describes the causes of autism

Study proposes a framework linking genes, metabolism and environment in autism — and may point to new ways to prevent or treat symptoms Peer-Reviewed Publication University of California – San Diego image: A “three-hit” metabolic signaling model that reframes autism as a treatable disorder of cellular communication and energy metabolism. view more   Credit: UC San Diego […]

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Engineers decode dementia type using AI and EEG brainwave analysis

by Florida Atlantic University edited by Lisa Lock, reviewed by Andrew Zinin  Editors’ notes EEG sensors record brain activity (left), generating brainwave signals (middle) that are analyzed by explainable AI (top right) and mapped onto brain regions (bottom right) to detect and interpret dementia type and severity noninvasively. Credit: Florida Atlantic University Dementia is a group of disorders

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Pulmonary fibrosis traced to key signaling pathway

by Jordan Shaked, Yale University edited by Stephanie Baum, reviewed by Robert Egan  Editors’ notes Credit: Sauler Lab / Yale School of Medicine Idiopathic pulmonary fibrosis (IPF) is a chronic disease in which healthy lung tissue is gradually replaced by scar tissue. While the early events that initiate this change are poorly understood, recent research suggests that the

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New sound therapy could help tinnitus sufferers via their smartphones

by Newcastle University edited by Lisa Lock, reviewed by Andrew Zinin  Editors’ notes Hearing correction profiles. Credit: Hearing Research (2025). DOI: 10.1016/j.heares.2025.109335 A pioneering study has unveiled a new sound therapy that reduces the loudness of tinnitus and has the potential to be delivered online using everyday devices like smartphones. The Newcastle University-led research works by introducing a sound modulation

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Disarming cancer stem cells’ shield makes immunotherapy more effective

by University of Chicago Medical Center edited by Lisa Lock, reviewed by Robert Egan  Editors’ notes Credit: Cancer Cell (2025). DOI: 10.1016/j.ccell.2025.11.001 Immunotherapy has revolutionized cancer care by training the immune system to detect and destroy tumors. For many patients, it works very well in shrinking tumors and sending cancer into remission, an undetectable state of cancer. But that remission

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Team discovers how to target ‘undruggable’ protein that fuels aggressive leukemia

by Denise Heady, University of California, Los Angeles edited by Lisa Lock, reviewed by Andrew Zinin  Editors’ notes B-lymphoblastic leukemia, a type of blood cancer. Credit: The Rao Laboratory. Researchers at the UCLA Health Jonsson Comprehensive Cancer Center have identified a small molecule that can inhibit a cancer-driving protein long considered impossible to target with drugs—a discovery that

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Dietary restriction fuels T cells with ketones, boosting their cancer-fighting stamina

by Beth Hinshaw, Van Andel Research Institute edited by Lisa Lock, reviewed by Robert Egan  Editors’ notes Credit: Pixabay/CC0 Public Domain Reducing calorie intake helps cancer-fighting immune cells do their jobs more effectively, reports a study by Van Andel Institute scientists and collaborators. The findings lay the groundwork for developing dietary strategies to boost the effects of a

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Q&A: Why knowing your family’s surgical history might be key to preventing emergency gallbladder surgery

by Rutgers University edited by Stephanie Baum, reviewed by Andrew Zinin  Editors’ notes Credit: Pixabay/CC0 Public Domain People might attribute midnight bouts of chest pain or waves of nausea to food poisoning, stress or a stubborn case of indigestion, but Rutgers Health researchers suggest that knowing your family’s surgical past could pinpoint another cause: gallstone disease. Their study, published in

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Swapping old sofas and chairs reduces body levels of harmful flame retardants

by Rebecca Fuoco, Green Science Policy Institute edited by Stephanie Baum, reviewed by Robert Egan  Editors’ notes Credit: Environmental Pollution (2025). DOI: 10.1016/j.envpol.2025.127326 New research led by the California Department of Public Health and partners has found that replacing foam-containing furniture made before 2014 would cut in half levels of certain harmful flame retardants in people’s bodies in just

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Machine learning models could help diagnose ALS earlier through blood biomarkers

by Noah Fromson, University of Michigan edited by Robert Egan  Editors’ notes Study design overview. Credit: Nature Communications (2025). DOI: 10.1038/s41467-025-64622-5 Using machine learning models, researchers at Michigan Medicine have identified a potential way to diagnose amyotrophic lateral sclerosis, or ALS, earlier from a blood sample, a study suggests. The models, which analyze blood for biomarkers through gene expression

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