Neural cells – artistic impression. Image credit: Alius Noreika / AI For years, scientists studying Parkinson’s and Alzheimer’s have been stuck with the same frustrating problem: the diseases happen deep inside the human brain, long before symptoms show up, and there has never been a reliable way to watch those earliest changes unfold. Animal models […]
Peer-Reviewed Publication University of Gothenburg image: Professor Andrei Chagin, Sahlgrenska Academy at the University of Gothenburg. view more Credit: Photo: Magnus Gotander Researchers at the University of Gothenburg can now demonstrate previously unexplained processes behind growth therapy. It involves hormonal mechanisms at the cellular level, with focus on a sensitive balance between stem cells and growth hormone.
A delicate balance between growth hormone and stem cells Read More »
The publicly-available library can be used to reveal a more accurate picture of what drugs are in a patient’s body than what is listed on their medical record. Peer-Reviewed Publication University of California – San Diego l image: Co-first authors Nina Zhao, Ph.D., and Kine Eide Kvitne, Ph.D., analyze biological samples with a mass spectrometer
New online tool detects drug exposure directly from patient samples Read More »
by Ellen T. Meiser, The Conversation edited by Christopher Packham, reviewed by Andrew Zinin Editors’ notes Credit: Unsplash/CC0 Public Domain The season of gifting is in full swing—a time when people scour the internet and shops of all kinds for items that appropriately symbolize their relationships with their loved ones. Gift givers hope that their gift will appropriately communicate their
by Lori Solomon edited by Robert Egan Editors’ notes The U.S. Food and Drug Administration has approved Itvisma (onasemnogene abeparvovec-brve) for the treatment of spinal muscular atrophy (SMA) in patients 2 years and older with confirmed mutation in the survival motor neuron 1 (SMN1) gene. Itvisma, an adeno-associated virus vector-based gene therapy, is administered with a
FDA approves Itvisma for spinal muscular atrophy Read More »
by St. Jude Children’s Research Hospital edited by Lisa Lock, reviewed by Robert Egan Editors’ notes LSM with ±s.e. for change from baseline in HFMSE score by visit. Credit: Nature Medicine (2025). DOI: 10.1038/s41591-025-04103-w A single-dose gene replacement therapy is found to improve movement ability in children over 2 years of age and teenagers with spinal muscular atrophy, according to
Gene therapy improves movement in kids with spinal muscular atrophy Read More »
by Temple University edited by Robert Egan Editors’ notes Credit: Artem Podrez from Pexels Measuring the lymphocytes—white blood cells that fight infection—in a patient’s blood can be used to predict outcomes in non-Hodgkin lymphoma patients who receive CAR T-cell therapy, according to research from physicians at Fox Chase Cancer Center and Temple Health. The study, published in the journal Blood and
A routine blood test could help predict who benefits most from CAR T-cell therapy Read More »
by University of Texas MD Anderson Cancer Center edited by Stephanie Baum, reviewed by Andrew Zinin Editors’ notes Credit: Pixabay/CC0 Public Domain In a recent preclinical study, researchers from The University of Texas MD Anderson Cancer Center developed an antibody therapy called 77A that showed an ability to overcome treatment resistance in blood cancers, such as myeloma and
New antibody boosts immune response against blood cancers and solid cancers Read More »
by University College London edited by Sadie Harley, reviewed by Robert Egan Editors’ notes Credit: Unsplash/CC0 Public Domain A new treatment using genome-edited immune cells, developed by scientists at UCL (University College London) and Great Ormond Street Hospital (GOSH), has shown promising results in helping children and adults fight a rare and aggressive form of blood cancer called
‘Ready-made’ T-cell gene therapy tackles ‘incurable’ T-cell leukemia Read More »
by Michele W Sequeira, University of New Mexico Cancer Center edited by Stephanie Baum, reviewed by Robert Egan Editors’ notes Ovarian cancer cells with activated Notch3 are more sensitive to auranofin. A, Western blot analysis of total cell lysates showing Notch3 and RBPJ levels in seven established ovarian cancer cell lines. Histone H3 was used as a loading
An existing drug may improve ovarian cancer treatment Read More »
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