December 8, 2025

Protective regimen allows successful stem cell transplant even without close genetic match between donor and recipient

December 8, 2025 / Research update / InnovateMed Author / stem cell transplant

by American Society of Hematology edited by Sadie Harley, reviewed by Andrew Zinin Editors’ notes Credit: Unsplash/CC0 Public Domain A new study shows that giving the chemotherapy drug cyclophosphamide after allogeneic hematopoietic cell transplantation, a curative treatment for common types of blood cancer, can make the procedure safe and effective even when donors and recipients are unrelated and have extensive […]

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IV iron improves survival, increases hemoglobin in patients with iron-deficiency anemia and acute infection

December 8, 2025 / Clinical Practice / InnovateMed Author / iron deficiency anaemia

by American Society of Hematology edited by Sadie Harley, reviewed by Andrew Zinin Editors’ notes Credit: Unsplash/CC0 Public Domain Treatment with intravenous (IV) iron significantly improved survival and increased hemoglobin levels in patients with iron-deficiency anemia who were hospitalized for an acute bacterial infection, according to an analysis of data from more than 85,000 patients. The study was

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Wireless device uses light patterns to deliver information directly to the brain

December 8, 2025 / Research update / InnovateMed Author / light patterns

by Northwestern University edited by Sadie Harley, reviewed by Andrew Zinin Editors’ notes The thin, flexible, wireless device sits next to a quarter for scale. Device emits complex patterns of light (shown here as an “N”) to transmit information directly to the brain. Credit: Mingzheng Wu/Northwestern University In a new leap for neurobiology and bioelectronics, Northwestern University scientists

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Black patients with AML are younger at diagnosis, experience poorer survival outcomes than white patients, data show

December 8, 2025 / Research update / InnovateMed Author / AML

by American Society of Hematology edited by Sadie Harley, reviewed by Andrew Zinin Editors’ notes Credit: Unsplash/CC0 Public Domain Compared with white patients, Black patients with acute myeloid leukemia (AML) were on average more than five years younger at diagnosis, more than 30% more likely to die of their disease, and more than 20% more likely to die

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Aging midbrain neurons face energy crisis linked to Parkinson’s

December 8, 2025 / Research update / InnovateMed Author / parkinson

by Weill Cornell Medical College edited by Lisa Lock, reviewed by Robert Egan Editors’ notes Glycogen synthase is expressed in dopaminergic axon terminals, enabling local glycogen storage. Credit: Proceedings of the National Academy of Sciences (2025). DOI: 10.1073/pnas.2523019122 Dopamine neurons in a part of the brain called the midbrain may, with aging, be increasingly susceptible to a vicious spiral of

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New findings support a chemo-free approach for treating Ph+ ALL

December 8, 2025 / Research update / InnovateMed Author / chemo free approach

by American Society of Hematology edited by Sadie Harley, reviewed by Andrew Zinin Editors’ notes Credit: Unsplash/CC0 Public Domain A chemotherapy-free combination treatment outperformed a combination of targeted therapy and chemotherapy among patients with Ph+ acute lymphoblastic leukemia (ALL) in a new study. The Phase III trial, which included adult patients with no upper age limit, is the

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Slow turning could be an indicator for Parkinson’s disease

December 8, 2025 / Research update / InnovateMed Author / parkinson

by Murdoch University edited by Lisa Lock, reviewed by Andrew Zinin Editors’ notes Credit: Pixabay/CC0 Public Domain An international study has found that wearable technology could help detect Parkinson’s disease (PD) up to nine years before clinical diagnosis simply by monitoring how people turn when they walk. The collaborative research, involving five institutions, including the University Hospital of

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Aza–ven combination outperforms standard care in AML patients eligible for intensive chemotherapy

December 8, 2025 / Research update / InnovateMed Author / AML

by American Society of Hematology edited by Sadie Harley, reviewed by Andrew Zinin Editors’ notes Acute myelocytic leukemia (AML). Credit: Unsplash/CC0 Public Domain In a new trial, patients newly diagnosed with acute myeloid leukemia (AML) fared significantly better with a combined regimen of azacitidine and venetoclax compared with conventional induction chemotherapy. The azacitidine–venetoclax combination (known as aza-ven) is

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TikTok videos mislead on epilepsy care, experts say

December 8, 2025 / Clinical Practice / InnovateMed Author / epilepsy

by Dennis Thompson edited by Sadie Harley, reviewed by Andrew Zinin Editors’ notes Fake clickbait TikTok videos about epilepsy treatments are receiving more views than accurate, evidence-based offerings, a new study says. More than half of TikTok videos regarding epilepsy featured claims that were false, misleading and potentially harmful, researchers reported Friday at the annual meeting of the American

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Depression increases epilepsy risk, makes it harder to treat

December 8, 2025 / Research update / InnovateMed Author / depression

by Dennis Thompson edited by Sadie Harley, reviewed by Andrew Zinin Editors’ notes People with depression have a more than doubled risk of developing epilepsy, a new study says. Worse, depression then makes epilepsy more difficult to treat, according to results of a second study. Both papers, presented at the annual meeting in Atlanta of the American Epilepsy

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