October 27, 2025

Online unsupervised Tai Chi intervention for knee pain and function in people with knee osteoarthritis

October 27, 2025 / Research update / InnovateMed Author / osteoarthritis

JAMA Internal Medicine Peer-Reviewed Publication JAMA Network About The Study: This randomized clinical trial found that this unsupervised multimodal online tai chi intervention improved knee pain and function compared with the control at 12 weeks. This free-to-access web-based intervention offers an effective, safe, accessible, and scalable option for guideline-recommended osteoarthritis exercise. Corresponding Author: To contact the corresponding […]

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Why does ALS take away body movement? The hidden burden that seals the fate of motor neurons

October 27, 2025 / Research update / InnovateMed Author / ALS, Amyotrophic Lateral Sclerosis

by Research Organization of Information and Systems edited by Sadie Harley, reviewed by Robert Egan Highly degradative (dark) cells in the spinal cord were identified as motor neurons. Credit: Kazuhide Asakawa, National Institute of Genetics ALS, also known as Lou Gehrig’s disease, is among the most challenging neurological disorders: relentlessly progressive, universally fatal, and without a cure

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Analysis finds alarming rise in severe diverticulitis among younger Americans

October 27, 2025 / Research update / InnovateMed Author / severe diverticulitis

by University of California, Los Angeles edited by Sadie Harley, reviewed by Alexander Pol Credit: Pixabay/CC0 Public Domain A comprehensive analysis of over 5.2 million hospitalizations reveals a troubling surge in severe diverticulitis cases among Americans younger than 50. The analysis, led by researchers from UCLA and Vanderbilt University and published in the journal Diseases in the Colon & Rectum,

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Improving immunotherapy responses to fight cancer with dual therapies

October 27, 2025 / Research update / InnovateMed Author / immunotherapy

by Naedine Hazell, Yale University edited by Lisa Lock, reviewed by Andrew Zinin Editors’ notes Anti–PD-1/anti-MIF improves survival and tumor responses. Credit: JCI Insight (2025). DOI: 10.1172/jci.insight.191539 Promising study in dual inhibition of PD1 and macrophage migration inhibitory factor Two therapies can be better than one for treating some cancers, concludes a Yale study published Oct. 22 in JCI Insight that finds promise in

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Scientists uncover new driver of ovarian cancer spread

October 27, 2025 / Research update / InnovateMed Author / ovarian cancer

by University of South Australia edited by Lisa Lock, reviewed by Robert Egan F2R protein expression in ovarian cancer tissues. Credit: International Journal of Molecular Sciences (2025). DOI: 10.3390/ijms26178529 Adelaide researchers have identified a promising new biomarker and treatment target for ovarian cancer that could markedly improve the outlook for women diagnosed with this aggressive disease. Ovarian cancer is the

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Henna’s hidden healing: Treating fibrosis with a chemical derived from Lawsonia inermis

October 27, 2025 / Research update / InnovateMed Author / Lawsonia inermis

by Osaka Metropolitan University edited by Sadie Harley, reviewed by Robert Egan Editors’ notes Treatment with Lawsone converts a liver with fibrosis into a healthy liver. Credit: Osaka Metropolitan University Lawsonia inermis is best known for making henna, a versatile dye that is used to change the color of skin and clothes. Now, researchers from Osaka Metropolitan University

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Mitochondria and lysosomes reprogram immune cells that dampen inflammation

October 27, 2025 / Research update / InnovateMed Author / dampen inflammation

Scientists at St. Jude Children’s Research Hospital discovered that metabolism controls regulatory T cells, the “brakes” of the immune system Peer-Reviewed Publication St. Jude Children’s Research Hospital image: (L) Corresponding author Hongbo Chi, PhD, Department of Immunology chair and Center of Excellence for Pediatric Immuno-Oncology (CEPIO) co-director and (R) first author Jordy Saravia, PhD, St.

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Blood immune cell analysis tested in patients shows promise for early Parkinson’s detection

October 27, 2025 / Research update / InnovateMed Author / parkinson detection

by Ángeles Gallar, Miguel Hernandez University of Elche edited by Sadie Harley, reviewed by Robert Egan In total, 22 genes showed differential expression between Parkinson’s patients and healthy volunteers. Some are involved in immune responses, supporting the hypothesis that inflammation and the immune system play a role in the disease’s development. Others are linked to molecular transport

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Combined HIV vaccines can act in concert to achieve diverse antibody priming

October 27, 2025 / Research update / InnovateMed Author / hiv vaccine

by Justin Jackson, Medical Xpress edited by Sadie Harley, reviewed by Robert Egan MPEM after multipriming immunization. A cocktail of N332-GT5 and ApexGT5 was used to form complexes with pooled serum IgG (digested to Fab) from triple mRNA-LNPs (high dose, D) or proteins (5 μg of N332-GT5, 5 μg of ApexGT5, and 10 μg of eOD-GT8, E) primed

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Common cholesterol drug might protect against ‘chemo brain’

October 27, 2025 / Research update / InnovateMed Author / chemo brain

by Dennis Thompson edited by Sadie Harley, reviewed by Andrew Zinin The most common cholesterol drug around might help protect cancer patients from “chemo brain.” Statins appeared to protect breast and lymphoma cancer patients’ brain function for up to two years after their cancer treatment, researchers report in JAMA Network Open. “Cancer treatment can be debilitating, and cognitive decline arising from chemotherapy

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