September 11, 2025

Tirzepatide- A novel therapeutic against metabolic dysfunction-associated steatotic liver disease (MASLD)

September 11, 2025 / Research update / InnovateMed Author / steatotic liver disease

Peer-Reviewed Publication Compuscript Ltd FacebookXLinkedInWeChatBlueskyMessageWhatsAppEmail image: Effect of tirzepatide treatment on body weight (A) and liver weight (B) in mice with MASLD. Representative images of liver appearance (C), histological analysis via hematoxylin‒eosin (HE) staining (D), and lipid accumulation assessment via Oil Red O staining (E) are shown. (F) HepG2 cells were incubated with 0.2% BSA, 0.2 mM PA, or 0.2 mM PA supplemented with […]

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C1ORF122: A novel diagnostic and prognostic biomarker in HCC

September 11, 2025 / Research update / InnovateMed Author / HCC

C1orf122 promotes HCC via the SRPK1-PI3K/AKT/GSK3β axis Peer-Reviewed Publication Compuscript Ltd image: (A) The abundance of C1orf122 in HCC and normal tissues was assessed using data from TCGA. (B) C1orf122 protein expression in seven pairs of tumor tissues (T) and matching non-cancerous tissues (N) as determined by Western blotting. (C) Immunohistochemistry labelling was performed to

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AI tools uncover new link between idiopathic pulmonary fibrosis and aging

September 11, 2025 / Research update / InnovateMed Author / pulmonary fibrosis

“Our findings establish novel connections between aging biology and IPF pathogenesis while demonstrating the potential of AI-guided approaches in therapeutic development for age-related diseases.” Peer-Reviewed Publication Impact Journals LLC image: Figure 2. Comparison of biological age predictions between healthy controls and cases of severe COVID-19 infection. (A) Proteomic aging clock shows R2=0.84 in the task of age

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Portable light-based brain monitor shows promise for dementia diagnosis

September 11, 2025 / Research update / InnovateMed Author / dementia diagnosis

Broadband near-infrared spectroscopy, a portable brain-monitoring tool, can detect metabolic changes linked to dementia by measuring cytochrome c oxidase activity Peer-Reviewed Publication SPIE–International Society for Optics and Photonics image: A noninvasive neuromonitoring technology uses broadband near-infrared spectroscopy to measure concentrations of oxidized cytochrome c oxidase (oxCCO), a metabolic mitochondrial enzyme linked to Alzheimer’s disease. A

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Genetic peptides that shape gut bacteria may protect against obesity and diabetes

September 11, 2025 / Research update / InnovateMed Author / diabetes, genetic peptides, obesity

by University of Sydney edited by Sadie Harley, reviewed by Robert Egan Schematic of murine defensin secretion from Paneth cells into the small intestine. Credit: The EMBO Journal (2025). DOI: 10.1038/s44318-025-00555-5 New research from the University of Sydney’s Charles Perkins Center has found that genes play an active role in shaping the bacteria found in our gut, questioning the idea

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Analysis of ‘magic mushroom’ edibles finds no psilocybin but many undisclosed active ingredients

September 11, 2025 / Patient education / InnovateMed Author / psilocybin

by Oregon State University edited by Sadie Harley, reviewed by Robert Egan Credit: Unsplash/CC0 Public Domain “Magic mushroom” edibles sold at smoke shops and convenience stores are likely to contain no psilocybin but instead a range of undisclosed active ingredients, a study led by an Oregon State University College of Pharmacy scientist shows. The research collaboration, which included a

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New study reveals a hidden risk after cervical cancer

September 11, 2025 / Clinical Practice / InnovateMed Author / cervical cancer

by Medical University of South Carolina edited by Stephanie Baum, reviewed by Robert Egan Credit: Pixabay/CC0 Public Domain For women who’ve overcome cervical cancer, new research from MUSC Hollings Cancer Center points to another health risk that may not be on their radar: anal cancer. Led by Hollings researchers Haluk Damgacioglu, Ph.D., and Ashish Deshmukh, Ph.D., co-leader

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Scientists pinpoint early warning stage before prediabetes

September 11, 2025 / Research update / InnovateMed Author / prediabetes

by Steven Lee, University of Texas at San Antonio edited by Gaby Clark, reviewed by Andrew Zinin Graphical Abstract. Credit: Diabetes Care (2025). DOI: 10.2337/dc24-2832 A study from The University of Texas at San Antonio Health Science Center indicates that changes in the body that lead to type 2 diabetes occur long before current diagnostic thresholds for prediabetes are

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Blue, green, brown, or something in between—the science of eye color explained

September 11, 2025 / Patient education / InnovateMed Author / eye color

by Davinia Beaver, The Conversation edited by Lisa Lock, reviewed by Andrew Zinin Credit: Unsplash/CC0 Public Domain You’re introduced to someone and your attention catches on their eyes. They might be a rich, earthy brown, a pale blue, or the rare green that shifts with every flicker of light. Eyes have a way of holding us, of

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New antibody cocktail shows promise for treating multiple strains of flu

September 11, 2025 / Research update / InnovateMed Author / flu

by Krystal Kasal, Phys.org edited by Gaby Clark, reviewed by Robert Egan Transmission electron micrograph of influenza A virus, late passage. Credit: CDC While vaccines can be very effective for preventing viruses, like the influenza A virus (IAV), they are often strain-specific and prone to viral escape mutations. IAV alone is responsible for around 500,000 deaths worldwide each

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