August 28, 2025

Depression linked to specific altered brain cells—findings open door to new treatments

August 28, 2025 / Research update / InnovateMed Author / depression

by Keila DePape, McGill University edited by Gaby Clark, reviewed by Robert Egan Chromatin architecture at the single-cell level. Credit: Nature Genetics (2025). DOI: 10.1038/s41588-025-02249-4 Researchers at McGill University and the Douglas Institute have identified two specific types of brain cells that are altered in people with depression. The study, published in Nature Genetics, opens the door to developing new […]

Depression linked to specific altered brain cells—findings open door to new treatments Read More »

High protein or Trp diet increases the risk of cancer-associated venous thromboembolism

August 28, 2025 / Research update / InnovateMed Author / venous thrombosis

by Boston University School of Medicine edited by Sadie Harley, reviewed by Andrew Zinin Credit: AI-generated image Next to cancer recurrence or progression, cardiovascular diseases are the leading causes of death in cancer survivors. The Surveillance, Epidemiology, and End Results database revealed that among the more than three million who initially survived cancer between 1973 and 2012,

High protein or Trp diet increases the risk of cancer-associated venous thromboembolism Read More »

People who skip breakfast and eat late dinners may have a higher risk of osteoporosis

August 28, 2025 / Patient education / InnovateMed Author / osteoporosis

by The Endocrine Society edited by Gaby Clark, reviewed by Andrew Zinin Credit: Unsplash/CC0 Public Domain People who skip breakfast and eat late dinners may have an increased risk of developing osteoporosis, according to a new study published in the Journal of the Endocrine Society. Lifestyle habits, such as exercise, alcohol consumption and smoking, are known to increase people’s risk of osteoporosis, however little

People who skip breakfast and eat late dinners may have a higher risk of osteoporosis Read More »

FDA approves updated Covid vaccines, including mRNA shots from Pfizer, Moderna

August 28, 2025 / News update / InnovateMed Author / covid vaccine

by Max Bayer The FDA on Wednesday approved updated formulas of the Covid-19 vaccines ahead of the fall respiratory season, though the labels are more limited than in years past. Vaccines were approved for Pfizer, Moderna and Novavax for all adults 65 and older and people younger than 65 who are at higher risk of

FDA approves updated Covid vaccines, including mRNA shots from Pfizer, Moderna Read More »

Metformin May Shield Against Dementia in Overweight/Obesity

August 28, 2025 / Research update / InnovateMed Author / metformin, obesity

TOPLINE: During a 10-year follow-up, metformin use was associated with significantly lower risks for both dementia and all-cause mortality in patients with overweight or obesity. METHODOLOGY: Metformin, the most widely prescribed glucose-lowering treatment, is linked to a reduced risk for dementia in patients with diabetes; however, its effect on the incidence of dementia among individuals

Metformin May Shield Against Dementia in Overweight/Obesity Read More »

Transplanted Islet Cells Survive Without Immune Suppression

August 28, 2025 / Research update / InnovateMed Author / immune suppression, transplanted islet

For the first time, researchers have transplanted gene-edited donor islet cells that secrete insulin in a person with type 1 diabetes (T1D) without the use of immunosuppression. Twelve-week results from the phase 1, single-participant study were published online on August 4, 2025, as a Brief Report in The New England Journal of Medicine. Six-month data were presented on

Transplanted Islet Cells Survive Without Immune Suppression Read More »

patient education – Diabetes in the Heat: Overlooked Risks That Could Cost Lives

August 28, 2025 / Clinical Practice, Patient education / InnovateMed Author / diabetes, heat waves

Current high temperatures can put significant stress on people with chronic illnesses, including those with diabetes, and may also affect diagnostics and therapy. Several experts explain what people with diabetes and their clinicians should pay attention to during extreme heat. High-Risk Groups “The body’s own temperature regulation is often impaired in people with diabetes. The

patient education – Diabetes in the Heat: Overlooked Risks That Could Cost Lives Read More »

Gut-Lung Axis: Implications and Clinical Relevance for Pulmonology

August 28, 2025 / Research update / InnovateMed Author / gut lung axis

Emerging insights into the gut-lung axis continue to open new possibilities for managing chronic respiratory diseases, from cystic fibrosis (CF) in the youngest patients to chronic obstructive pulmonary disease (COPD) in older adults. Despite growing evidence linking gut health to respiratory disease pathogenesis, these findings are not yet ready for routine clinical application. Still, they underscore the

Gut-Lung Axis: Implications and Clinical Relevance for Pulmonology Read More »

First enzyme-targeting drug reverses damage in metabolic fatty liver disease

August 28, 2025 / Research update / InnovateMed Author / metabolic fatty liver disease

by University of California – San Diego edited by Gaby Clark, reviewed by Robert Egan Credit: CC0 Public Domain Researchers at the University of California San Diego School of Medicine have identified a new investigational drug that shows promise in treating metabolic dysfunction-associated steatohepatitis (MASH), a serious form of fatty liver disease linked to obesity and type 2

First enzyme-targeting drug reverses damage in metabolic fatty liver disease Read More »

New treatment with designer proteins could disrupt cycle of addiction without stifling natural pleasure

August 28, 2025 / Research update / InnovateMed Author / protein

by Miles Martin, University of California – San Diego edited by Lisa Lock, reviewed by Andrew Zinin Chimeric ion channels that are activated by cocaine. Credit: Nature (2025). DOI: 10.1038/s41586-025-09427-8 A new biochemical approach to combat addiction, developed by researchers at the University of California San Diego and the National Institute on Drug Abuse (NIDA), has shown promising results

New treatment with designer proteins could disrupt cycle of addiction without stifling natural pleasure Read More »