August 21, 2025

Fat-trapping microbeads provide drug-free weight loss in rats

by American Chemical Society edited by Sadie Harley, reviewed by Robert Egan   These plant-based microbeads absorb and trap fat. Credit: Yue Wu Weight-loss interventions, including gastric bypass surgery and drugs that prevent dietary fat absorption, can be invasive or have negative side effects. Now, researchers have developed edible microbeads made from green tea polyphenols, vitamin E and […]

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Key genes that act as a brake on blood cancer growth reveal potential treatment targets

by La Trobe University edited by Lisa Lock, reviewed by Robert Egan Credit: CC0 Public Domain Australian researchers have used an innovative genome-wide screening approach to identify genes, and their encoded proteins, that play critical roles in the prevention of lymphoma development, revealing new potential treatment targets for these blood cancers. The study, published in Nature Communications, has identified

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Vaginal estrogen tablets may be safe for postmenopausal women who have had a stroke

by American Heart Association edited by Sadie Harley, reviewed by Robert Egan Credit: Pixabay/CC0 Public Domain Using vaginal estrogen tablets was not associated with an increased risk of recurrent ischemic stroke among postmenopausal women in a registry in Denmark, according to research published in Stroke. Unlike oral estrogen or transdermal formulations such as creams and patches, the women in this registry-based

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Study finds adults with hearing loss using hearing aids have reduced dementia risk

by Elana Gotkine edited by Sadie Harley, reviewed by Alexander Pol Adults with hearing loss (HL) with hearing aids have a reduced risk for dementia, according to a research letter published in JAMA Neurology. Lily Francis, M.B.B.S., from the University of Texas Health Science Center at San Antonio, and colleagues conducted a prospective association study to examine whether hearing aid

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A simple test could predict a newborn’s risk of developing type 2 diabetes

by Baker Heart & Diabetes Institute edited by Sadie Harley, reviewed by Andrew Zinin   Graphical abstract. Credit: Diabetes (2025). DOI: 10.2337/db25-0105 A genetic test of cord blood at birth may hold the key to predicting a child’s future risk of developing type 2 diabetes, according to exciting new research from Australia and Hong Kong. By analyzing the DNA in

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Repackaged cancer drug boosts delivery to tumors, improves combination therapies

by University of Arizona edited by Sadie Harley, reviewed by Robert Egan   SM-derived PTX self-assembled into paclitaxome. Credit: Nature Cancer (2025). DOI: 10.1038/s43018-025-01029-7 University of Arizona researchers devised a new method to deliver cancer chemotherapy drugs to pancreatic and breast cancer tumors more effectively and with less damage to healthy tissues than standard forms of chemotherapy. The paper is published in Nature

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Broccoli can have a protective effect against colon cancer, study reveals

by Sanjukta Mondal, Phys.org edited by Sadie Harley, reviewed by Robert Egan Higher intake of cruciferous vegetables is associated with a 20% lower risk of colon cancer. Credit: Sheila Sund for pxhere.com. pxhere.com/ko/photo/521526?utm_content=shareClip&utm_medium=referral&utm_source=pxhere The broccoli and Brussels sprouts that often get pushed to the edge of the plate might aid in reducing the risk of colon cancer. Colon

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New study maps out the timeline of DNA damage for multiple myeloma

by Sylvester Comprehensive Cancer Center edited by Lisa Lock, reviewed by Robert Egan Molecular time and temporal relationship between large chromosomal gains in multiple myeloma. Credit: Nature Genetics (2025). DOI: 10.1038/s41588-025-02292-1 A new study focused on multiple myeloma, the second most common blood cancer, may lead to better ways to group patients by the state of their DNA and define

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As Sarepta fights for Duchenne therapy, another group of patients feels left behind

Sarepta Therapeutics is fighting to salvage its Duchenne therapy Elevidys amid safety setbacks. But families of children with another condition, limb-girdle muscular dystrophy, say they’ve been abandoned by the company, which recently scrapped nearly a decade of work on gene therapies for the disease. The decision has devastated parents, many of whom uprooted their lives

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Pill That Slows Aging? Meds May Boost Health Span

Aging is the strongest risk factor for most chronic diseases; however, medicine has historically treated each condition individually. Geroscience is a new discipline that aims to define and modify aging-related biological pathways, slow age-related disability, prevent age-related diseases, and increase disability-free survival. A review in JAMA outlines the aims, methods, recent advances, and ongoing challenges of geroscience. The

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