tumor

Newly defined benign soft tissue tumor with bony shell may mimic malignancy

by Michael E. Newman, Johns Hopkins University School of Medicine edited by Stephanie Baum, reviewed by Robert Egan  Editors’ notes An example of an OSET (Ossifying Spindled and Epithelioid Tumor), a newly discovered and classified benign soft tissue tumor. Here, the OSET is seen as a surgically excised gross specimen (upper left) and in the specimen radiograph (lower […]

Newly defined benign soft tissue tumor with bony shell may mimic malignancy Read More »

Experimental cancer drug shows exceptional tumor-fighting potential

by Medical University of Vienna edited by Gaby Clark, reviewed by Robert Egan  Editors’ notes LiPyDau treatment inhibits the growth of a patient-derived lung adenocarcinoma xenograft. Credit: Molecular Cancer (2025). DOI: 10.1186/s12943-025-02444-1 A research team has developed a new chemotherapeutic agent, LiPyDau, which shows remarkable efficacy against multiple tumor types in preclinical studies. Published in the journal Molecular Cancer, the study introduces a

Experimental cancer drug shows exceptional tumor-fighting potential Read More »

Engineered stem cells yield millions of tumor-fighting natural killer cells at reduced cost

by Li Yali, Chinese Academy of Sciences edited by Sadie Harley, reviewed by Robert Egan  Editors’ notes Overview of the method for large-scale production of iNK and CAR-iNK cells from cord blood CD34+ hematopoietic stem and progenitor cells. Credit: Prof. Wang’s Lab Chinese researchers have developed a novel method to efficiently engineer natural killer (NK) cells for cancer immunotherapy.

Engineered stem cells yield millions of tumor-fighting natural killer cells at reduced cost Read More »

When Tumors Vanish: The Mystery of Spontaneous Regression – cancer

Julia Senn October 06, 2025 Spontaneous regression of cancer is an uncommon event observed most often in neuroblastoma, leukemia, lung cancer, and melanoma. The underlying mechanisms are not fully understood; however, infections and immune system activation may contribute to treatment development. Historical Observations In 1891, William B. Coley, a surgeon, reported the disappearance of recurrent spindle cell

When Tumors Vanish: The Mystery of Spontaneous Regression – cancer Read More »

Repackaged cancer drug boosts delivery to tumors, improves combination therapies

by University of Arizona edited by Sadie Harley, reviewed by Robert Egan   SM-derived PTX self-assembled into paclitaxome. Credit: Nature Cancer (2025). DOI: 10.1038/s43018-025-01029-7 University of Arizona researchers devised a new method to deliver cancer chemotherapy drugs to pancreatic and breast cancer tumors more effectively and with less damage to healthy tissues than standard forms of chemotherapy. The paper is published in Nature

Repackaged cancer drug boosts delivery to tumors, improves combination therapies Read More »

Satri-cel study marks first randomized CAR T-cell success in solid tumors

by Justin Jackson, Phys.org edited by Sadie Harley, reviewed by Robert Egan   Credit: Pixabay/CC0 Public Domain Satri-cel, a CLDN18.2-targeted CAR T-cell therapy, nearly doubles progression-free survival in patients with previously treated gastric or gastro-esophageal junction cancer, according to a multicenter randomized trial led by Peking University Cancer Hospital in China. Gastric and gastro-esophageal junction cancers remain among

Satri-cel study marks first randomized CAR T-cell success in solid tumors Read More »

Scroll to Top