July 2025

ACG Updates Guidance on Crohn’s Disease Management

The American College of Gastroenterology (ACG) has issued updated guidance on the management of Crohn’s disease (CD) that reflects the surge in development of therapeutic options available since 2018, when the last guideline was published. These newer treatment options include interleukin-23 (IL-23) blockers risankizumab, mirikizumab, and guselkumab; the anti-IL-12/23 agent ustekinumab; the Janus kinase inhibitor […]

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Mapping the dairy matrix: How the physical structures in dairy foods uniquely fuel the human body

by Eileen Leahy, Elsevier edited by Lisa Lock, reviewed by Andrew Zinin Credit: CC0 Public Domain How do we determine how healthy our food is? We know now that our nutrition shouldn’t just be measured in calories, or even in just macronutrients (the balance of fats, protein, and carbohydrates). An emerging body of research is instead demonstrating that

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The Longevity Paradox: Medicine Meets Silicon Valley

For without friends, no one would choose to live.” – Aristotle Jeffrey Benabio, MD, MBA Last year, Bryan Johnson, a 46-year-old tech founder, spent 2 million dollars on a regimen that included monthly plasma transfusions from his teenage son. Why? Well, we live in an age when the wealthy inject themselves with young blood, undergo

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How Common Meds Secretly Wreck Your Patients’ Microbiome?

Effective ways to combat harmful viruses, bacteria, fungi, and parasitic worms have driven major advances in medicine and contributed to a significant increase in human life expectancy over the past century. However, as knowledge about the role of these microorganisms in promoting and maintaining health deepens, there is a need for a new look at

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Parkinson’s drug reduces symptoms in treatment-resistant depression, clinical trial finds

by University of Oxford edited by Lisa Lock, reviewed by Robert Egan   Primary efficacy assessment of change from baseline in QIDS-SR16 total score at week 12. Credit: The Lancet Psychiatry (2025). DOI: 10.1016/S2215-0366(25)00194-4. https://www.thelancet.com/journals/lanpsy/article/PIIS2215-0366(25)00194-4/fulltext A drug used for Parkinson’s disease has been shown to be effective in reducing the symptoms of difficult to treat depression, according to a study led

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Discovery of key brain repair mechanism in vascular dementia reveals promising therapeutic target

by University of California, Los Angeles edited by Sadie Harley, reviewed by Robert Egan   Credit: CC0 Public Domain A new study from UCLA Health has uncovered how inflammation in brain blood vessels exacerbates damage in vascular dementia and demonstrated that targeting this process with a repurposed drug can promote brain repair and functional recovery in mice. Published

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Landmark study investigates potential of Ambroxol, a cough medicine, to slow Parkinson’s-related dementia

Researchers at Lawson Research Institute are studying Ambroxol – a common cough medicine in Europe – as a potential treatment for dementia linked to Parkinson’s disease Peer-Reviewed Publication Lawson Research Institute image: Dr. Stephen Pasternak, cognitive neurologist at Lawson Research Institute of St. Joseph’s Health Care London, is lead author of a study suggesting Ambroxol,

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Traditional Medicare to add prior authorizations

  By Maya Goldman Illustration: Sarah Grillo/Axios Traditional Medicare is requiring more pre-treatment approvals in a bid to root out unnecessary care. The big picture: Medicare’s fee-for-service program hasn’t required prior authorizations to access most drugs or services, a major perk for enrollees. Prior authorization in privately run Medicare Advantage plans has become a hot-button issue for Congress

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