resistant depression

by Tamara Schneider and Claire Gauen, Washington University in St. Louis edited by Lisa Lock, reviewed by Andrew Zinin Credit: Monica Duwel/WashU Starting in your brainstem and meandering down your body, two branches of an information highway connect to your chest, heart, lungs, abdomen and intestines. These conduits, called the vagus nerves, pass signals back and forth between […]

by University of Oxford edited by Lisa Lock, reviewed by Robert Egan   Primary efficacy assessment of change from baseline in QIDS-SR16 total score at week 12. Credit: The Lancet Psychiatry (2025). DOI: 10.1016/S2215-0366(25)00194-4. https://www.thelancet.com/journals/lanpsy/article/PIIS2215-0366(25)00194-4/fulltext A drug used for Parkinson’s disease has been shown to be effective in reducing the symptoms of difficult to treat depression, according to a study led

by Ingrid Fadelli, Phys.org edited by Gaby Clark, reviewed by Robert Egan   Graphical abstract summarizing the researchers’ review paper. Credit: Nagpurkar et al. (Neuroscience, 2025). Depression, characterized by persistent sadness, hopelessness and a lack of interest in previously enjoyed activities, is one of the most common mental health disorders. Recent estimates by the World Health Organization (WHO) suggest