July 22, 2025

Dementia risk does not differ with GLP-1 RAs, DPP4is for seniors with type 2 diabetes, study finds

by Elana Gotkine edited by Sadie Harley, reviewed by Andrew Zinin For older adults with diabetes, there is no clear evidence to suggest that the incidence of dementia differs for those using glucagon-like peptide 1 receptor agonists (GLP-1 RAs) versus dipeptidyl peptidase-4 inhibitors (DPP4is), according to a study published online in the Annals of Internal Medicine. Kosuke Inoue, M.D., Ph.D., […]

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Probiotics can help or hinder gut recovery after antibiotic treatment

by Tracey Peake, North Carolina State University edited by Stephanie Baum, reviewed by Andrew Zinin An antibiotic-treated mouse model that measures the return of colonization resistance after probiotic administration. Schematic of the mouse model monitoring colonization resistance after antibiotic treatment. All mice (n = 32) received cefoperazone in their drinking water for 5 days. Mice were orally gavaged at

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Radiation therapy overcomes immunotherapy resistance in some cancers

by Johns Hopkins University School of Medicine edited by Sadie Harley, reviewed by Andrew Zinin Cancer-immune cell interactions. Credit: Katerina Karaindrou x DALL-E By sparking the immune system into action, radiation therapy makes certain tumors that resist immunotherapy susceptible to the treatment, leading to positive outcomes for patients, according to new research by investigators at the Johns Hopkins

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Japanese drinkers’ response to alcohol can be divided into three distinct clusters

by RIKEN edited by Lisa Lock, reviewed by Andrew Zinin Cluster subgrouping of participants into three clusters. Credit: Neuropsychopharmacology (2025). DOI: 10.1038/s41386-025-02147-7 Researchers from the RIKEN Center for Integrative Medical Sciences in Japan and collaborators have used genetic analysis and experiments to discover that the subjective responses of Japanese people to alcohol can be divided into three clear clusters. This

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New diagnostic breakthrough predicts which head and neck cancer patients can be cured with surgery alone

by University of Turku edited by Lisa Lock, reviewed by Andrew Zinin Credit: EMBO Molecular Medicine (2025). DOI: 10.1038/s44321-025-00266-8 Researchers from the University of Turku and Turku University Hospital, Finland, led by Docent Sami Ventelä and Professor Jukka Westermarck, have developed a diagnostic tool that can revolutionize the treatment guidance of head and neck squamous cell carcinoma. Their study, recently published in EMBO

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New insights into the immune system’s crucial role in wound healing

by Mike Addelman, University of Manchester edited by Lisa Lock, reviewed by Andrew Zinin Credit: British Journal of Dermatology (2025). DOI: 10.1093/bjd/ljaf223 An enzyme expressed by skin cells could be helpful in the management of non-healing skin wounds and ulcers, according to research by University of Manchester and Singapore’s A*STAR Skin Research Lab scientists. Approximately 1 in 50 people will

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Post-COVID-related lung abnormalities almost always regress, consensus statement indicates

by Catholic University of the Sacred Heart edited by Sadie Harley, reviewed by Andrew Zinin Credit: Pixabay/CC0 Public Domain Visible on chest CT scans, post-COVID-19 residual lung abnormalities, which affect up to 50% of patients who have had an infection requiring hospitalization, may be associated with persistent or progressive respiratory symptoms and are often related to changes in

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New Guidelines Address Preexisting Diabetes and Pregnancy

SAN FRANCISCO — A new joint clinical practice guideline (CPG) from two endocrinology societies addresses managing preexisting diabetes and pregnancy, starting with a call to screen for pregnancy intention at every clinical encounter. “The lack of preconception care for patients with preexisting diabetes is a major focus of this guideline. We know from strong meta-analyses that there

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Endocrine Society Statement Outlines Knowledge Gaps in T1D – diabetes

A new Endocrine Society scientific statement outlines “challenges and opportunities” in understanding the pathogenesis of type 1 diabetes (T1D), with some clinical takeaways regarding the heterogeneity of the condition and the need for increased screening for preclinical disease. The statement was published on July 9, 2025 in The Journal of Clinical Endocrinology & Metabolism and will be presented on

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Why are women twice as likely to develop Alzheimer’s as men?

Andrzej Wojcicki/Getty Images Alvin Powell Harvard Staff Writer July 7, 2025 7 min read Researchers focusing on chromosomes, menopause A neglected piece of the Alzheimer’s puzzle has been getting increased scientific attention: why women are twice as likely as men to develop the disease. One might be tempted to explain the disparity as a natural consequence of

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