cancer cells

‘Barfing’ cancer cells and the promise of an anomalous protein

The discovery of an unusual protein on the surface of cancer cells may provide scientists with an ideal immunotherapy target for solid tumors, according to a study published yesterday in Science. Most immunotherapies work by drawing the immune system to a particular marker on the surface of a cancer cell in order to destroy those cells. This […]

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Researchers build new antibody to target cancer cells

A cancer-targeting antibody that helps the body’s immune cells spot and destroy hard-to-treat tumours such as triple-negative breast cancer has been developed by researchers. An electron microscope image showing a tumour cell breaking up and dying (dark red and orange) after being attacked by a natural killer cell on left (red). Image credit: The University

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Shelf-stable mRNA delivery system targets bladder cancer cells without immune response

by Steve Martin, Purdue University edited by Andrew Zinin  Editors’ notes  The GIST Add as preferred source Conceptual diagram of the initial electrostatic condensation step for mRNA complexation with CD-PLR10 followed by ELP coating to form LENN via hydrophobic host:guest interactions between the ELP prosthetic groups and the cyclodextrin cavities. Credit: Proceedings of the National Academy of Sciences (2026).

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Pressure flips the switch on cancer cells: How confinement drives epigenetic changes

by Ludwig Cancer Research edited by Robert Egan   Perinuclear acetylated tubulin cage assembles in response to confinement. Credit: Nature (2025). DOI: 10.1038/s41586-025-09445-6 Cancer cells are notoriously flexible, taking on new features as they move around the body. Many of these changes are due to epigenetic modifications, which influence how DNA is packaged, and not due to mutations in

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Detecting cancer cells in blood: the development of microchannel devices with microcone arrays

Researchers utilize engraved polycarbonate sheets and antibody coatings to efficiently capture cancer cells Peer-Reviewed PublicationChiba University image: By imprinting microcones on polycarbonate sheets followed by coating with human epithelial cell adhesion molecule antibodies, scientists from Japan have developed a microchannel-based diagnostic tool. Their device demonstrated high sensitivity while maintaining a capture efficiency of more than

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Researcher uses light to target and kill cancer cells

by Kate Rix, Northeastern University edited by Lisa Lock, reviewed by Andrew Zinin  Triple negative breast cancer and melanoma are typically resistant to chemotherapy, says Fleury Augustin Nsole Biteghe. But by attaching a light-sensitive drug to a protein in the cancer cells, and bathing the drug-infused protein in near-infrared light, the cancer cells die. Credit: Matthew Modoono/Northeastern University

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AI platform designs molecular missiles to attack cancer cells

A new method can produce custom-designed proteins in just 4-6 weeks that can arm the T cells of the body’s immune system to attack and kill cancer cells Peer-Reviewed Publication Technical University of Denmark image: A new AI-based method can produce specially designed proteins in just a few weeks that can arm the T cells

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Blocking a key enzyme could rewire cancer cells and suppress tumor growth

by Johns Hopkins University School of Medicine edited by Lisa Lock, reviewed by Robert Egan   The discovery shows that the production of ribosomal RNA (rRNA) is connected to how cells manage RNA splicing (a process that edits RNA). In studies of cancer cell lines using drugs that block rRNA production, a new stress response pathway was revealed.

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