New use for old drug: study finds potential of heart drug for treating growth disorders

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Researchers show that phosphodiesterase 3 inhibitors can promote bone growth by stimulating C-type natriuretic peptide signaling Ritsumeikan University image: Researchers have found that phosphodiesterase 3 (PDE3) inhibitors can boost long bone growth. Conventionally used to treat heart disease, thrombosis, and asthma, PDE3 inhibitors can stimulate the C-type natriuretic peptide (CNP) signaling in bone cells, activating […]

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