Spectacular breakthrough in sepsis research: Vitamin B1 stops deadly lactate production and opens the door to a new treatment

  Vlaams Instituut voor Biotechnologie Ghent, July 29, 2025 – Scientists in Ghent have achieved a major breakthrough in sepsis research. In a study on mice, the researchers demonstrate that vitamin B1 (thiamine pyrophosphate, TPP) restores mitochondrial energy metabolism, drastically reduces lactate production, and increases survival rates in sepsis. The study results were published in Cell Reports. […]

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