How urinary tract infections can trigger delirium and worsen dementia
by Kelsie Sandoval, Cedars-Sinai Medical Center edited by Lisa Lock, reviewed by Alexander Pol Editors’ notes The GIST Add as preferred source Urinary tract infection induces host IL-6 response. IL-6 complexes with the soluble IL-6 receptor in the periphery and initiates IL-6 trans-signaling via the glycoprotein 130 transmembrane (gp130) receptor on neurons, resulting in neuroinflammation and neuronal apoptosis. […]
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