Growing Comfortable With Diagnostic Uncertainty and ‘I Don’t Know’

Noor F. Shaik, MD, PhD DISCLOSURES February 05, 2026 When I was younger, one of my favorite TV shows was Mystery Diagnosis. I was captivated by the unfolding drama: a string of baffling symptoms, test after test negative, treatments failing — until, finally, a breakthrough. I breathed a sigh of relief when the patient appeared beside the […]

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