trizepatide

Tirzepatide May Suppress Brain Signals Tied to Food Cravings

/ Research update / /

Marilynn Larkin November 19, 2025   TOPLINE: A first-in-human study suggested that tirzepatide — a dual GLP-1 and glucose-dependent insulinotropic polypeptide (GIP) receptor agonist — modulated abnormal activity in the brain’s nucleus accumbens, thereby reducing food cravings and inducing weight loss in a patient with severe obesity. METHODOLOGY: Brain signals (known as delta-theta activity) in […]

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Semaglutide or tirzepatide and optic nerve and visual pathway disorders in type 2 diabetes

/ Research update / / , , ,

JAMA Network Open Peer-Reviewed Publication JAMA NETWORK About The Study: In this study of patients with type 2 diabetes who had no prior eye disorders, patients prescribed semaglutide or tirzepatide had an increased risk of nonarteritic anterior ischemic optic neuropathy and other optic nerve disorders, although the overall risk was low. These findings highlight the need

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