schizophrenia

About The Study: The results of this randomized clinical trial show that adjunctive semaglutide significantly improved glycemic control and weight outcomes in individuals with schizophrenia spectrum disorders. Secondary outcomes were exploratory. These findings support the use of glucagon-like peptide–1 receptor agonists (GLP-1RAs) as a potential early intervention strategy to reduce cardiometabolic risk in this vulnerable population. […]

Peer-Reviewed Publication University of Edinburgh A commonly prescribed antibiotic could help reduce the risk of some young people developing schizophrenia, new research suggests. Experts found that patients of adolescent mental health services who were treated with the antibiotic doxycycline were significantly less likely to go on to develop schizophrenia in adulthood compared with patients treated

by Ingrid Fadelli, Phys.org edited by Gaby Clark, reviewed by Robert Egan  Editors’ notes Overview of the team’s hypotheses. The researchers combined magnetic susceptibility (rises with iron, falls with myelin) with mean diffusivity (higher values = less myelin) and susceptibility anisotropy (higher values = more myelin) to test whether lower magnetic susceptibility in schizophrenia reflects excess myelin (hypothesis

by Nicolas Posunko, Skolkovo Institute of Science and Technology edited by Sadie Harley, reviewed by Robert Egan  Editors’ notes Basic outline of the study: Blood samples of healthy individuals and patients diagnosed with schizophrenia or major depressive disorder from two Russian cities were analyzed using a mass spectrometer to identify biological markers characterizing each of the diseases. Credit:

Peer-Reviewed Publication American College of Physicians Embargoed for release until 5:00 p.m. ET on Monday 25 August 2025 Follow @Annalsofim on X, Facebook, Instagram, Bluesky, and Linkedin Below please find summaries of new articles that will be published in the next issue of Annals of Internal Medicine. The summaries are not intended to substitute for the full articles as a source

by Cardiff University edited by Robert Egan Schizophrenia GWAS locus plot for KLC1. Credit: Nature Communications (2025). DOI: 10.1038/s41467-025-62429-y Researchers have discovered eight new genes associated with schizophrenia, in the largest exome-sequencing study of the disorder ever conducted. The breakthrough, made by scientists at the Centre for Neuropsychiatric Genetics and Genomics (CNGG) at Cardiff University, provides new information and

New findings published in Neuropsychopharmacology are the first to demonstrate that evenamide targets the key site of schizophrenia pathology in the hippocampus, and so could be an ideal therapeutic agent for treatment of the disorder Peer-Reviewed Publication LAVOIEHEALTHSCIENCE FacebookXLinkedInWeChatBlueskyMessageWhatsAppEmail Ad hoc announcement pursuant to Art. 53 LR New findings published in Neuropsychopharmacology are the first