Reversing fibrosis: New research provides insight for novel therapies

by Isabella Backman, Yale School of Medicine edited by Sadie Harley, reviewed by Robert Egan  Editors’ notes Model of keratinocyte-derived high affinity EGFR ligands to activate EGFR-STAT1 signaling in profibrotic fibroblasts. Credit: Nature Communications (2025). DOI: 10.1038/s41467-025-64648-9 Yale School of Medicine (YSM) researchers have made key breakthroughs in understanding how to treat fibrotic diseases such as scleroderma and graft-versus-host disease. […]

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