Polyploidy-induced senescence may drive aging, tissue repair, and cancer risk
Our work highlights the need to study polyploidy and senescence in concert to understand their roles in aging, cancer, and therapeutic resistance.” Peer-Reviewed PublicationImpact Journals LLC image: Figure 1. Polyploidy-induced senescence and its potential role in bladder dysfunction and carcinogenesis. (A) Polyploid bladder superficial uroepithelial cells (“Umbrella Cells”) at the bladder-urine interface exhibit markers of cellular senescence […]
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