Scientists reveal how a key inflammatory molecule triggers esophageal muscle contraction

by Toho University edited by Sadie Harley, reviewed by Andrew Zinin The contractile responses of esophageal smooth muscle (SM) induced by platelet-activating factor (PAF) involve the activation of L-type voltage-dependent calcium channels (L-type VDCCs), receptor-operated calcium channels (ROCCs), and store-operated calcium channels (SOCCs), with Orai1 serving as a key component of the SOCC pathway. Credit: Keisuke Obara A […]

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