nanoparticles

Size-shifting nanoparticles successfully deliver mRNA medicine to the pancreas

by Paul Arnold, Phys.org edited by Gaby Clark, reviewed by Robert Egan  Editors’ notes  The GIST Add as preferred source The role of capsules in organ-targeted delivery. Credit: Nature (2026). DOI: 10.1038/s41586-026-10158-7 In recent years, mRNA in lipid nanoparticles (mRNA–LNPs) has emerged as a promising strategy for treating numerous conditions, including COVID-19, various cancers and chronic genetic disorders. To date, […]

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New nanoparticle technology offers hope for hard-to-treat diseases –

A newly published paper in Nature Nanotechnology details groundbreaking nanoparticle technology, with research led by UTS Chair Professor in Nanomedicine Bingyang Shi. Nanoparticle – illustrative photo. Image credit: Pixabay (Free Pixabay license) A newly published perspective article in Nature Nanotechnology details groundbreaking nanoparticle technology to eliminate harmful, disease-causing proteins in the body. The technology marks a transformative

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How lipid nanoparticles carrying vaccines release their cargo

by Friedrich–Alexander University Erlangen–Nurnberg edited by Gaby Clark, reviewed by Robert Egan  Editors’ notes  The GIST Add as preferred source Membrane structure of lipid nanoparticles at an acidic pH value of 5. Positively charged amino lipids are blue, uncharged amino lipids yellow. Credit: Friedrich–Alexander University Erlangen–Nurnberg A study from FAU has shown that lipid nanoparticles restructure their membrane

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New nanoparticle mRNA vaccine may be cheaper and 100 times more powerful

By Malcolm Azania November 14, 2025 Facebook Twitter LinkedIn Reddit Flipboard Email Unit-per-unit, the experimental nanoparticle-enhanced mRNA vaccine reportedly does the work of a hundred times as much of its FDA-approved equivalent Depositphotos View 1 Images Researchers at MIT have just developed a new lipid nanoparticle that super-enhances the effectiveness of the mRNA vaccine in mice

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Nanoparticles that enhance mRNA delivery could reduce vaccine dosage and costs

by Massachusetts Institute of Technology edited by Sadie Harley, reviewed by Robert Egan  Editors’ notes AMG library synthesis and screening. Credit: Nature Nanotechnology (2025). DOI: 10.1038/s41565-025-02044-6 A new delivery particle developed at MIT could make mRNA vaccines more effective and potentially lower the cost per vaccine dose. In studies in mice, the researchers showed that an mRNA influenza vaccine delivered

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CRISPR’s efficiency triples with DNA-wrapped nanoparticles

With the power to rewrite the genetic code underlying countless diseases, CRISPR holds immense promise to revolutionize medicine. But until scientists can deliver its gene-editing machinery safely and efficiently into relevant cells and tissues, that promise will remain out of reach. An artistic interpretation of a spherical nucleic acid (SNA) nanoparticle, carrying CRISPR cargo, entering

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Protein–polymer nanoparticles can carry higher drug loads with improved stability

by Xi’an jiaotong-Liverpool University edited by Sadie Harley, reviewed by Robert Egan   A new nanoparticle made from the medical polymer PLGA and the blood protein albumin can carry higher doses of drugs and remain stable longer, offering improved delivery and fewer side effects. Credit: Lin, et al. pubs.acs.org/doi/10.1021/acsami.5c07710 Scientists at Xi’an Jiaotong-Liverpool University (XJTLU) and Nanjing University

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Stealthy’ lipid nanoparticles give mRNA vaccines makeover

Peer-Reviewed PublicationCornell University FacebookXLinkedInWeChatBlueskyMessageWhatsAppEmail ITHACA, N.Y. – A new material developed at Cornell University could significantly improve the delivery and effectiveness of mRNA vaccines by replacing a commonly used ingredient that may trigger unwanted immune responses in some people. Thanks to their ability to train cells to produce virus-killing proteins, mRNA vaccines have gained popularity

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