myeloma

How CAR T-cell therapies target myeloma at the molecular level

by Anne Grimm, Leipzig University edited by Gaby Clark, reviewed by Robert Egan  Editors’ notes Graphical abstract. Credit: Cancer Cell (2025). DOI: 10.1016/j.ccell.2025.10.014 In multiple myeloma, plasma cells proliferate uncontrollably in the bone marrow, disrupting the growth of healthy blood-forming cells. If the disease recurs after treatment or fails to respond, CAR T-cell therapy may be considered. In this innovative […]

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Single-dose CAR-T therapy potentially curative in multiple myeloma

by Justin Jackson, Phys.org edited by Sadie Harley, reviewed by Robert Egan   Micrograph of a plasmacytoma, the histologic correlate of multiple myeloma. H&E stain. Credit: Wikipedia/CC BY-SA 3.0 A multi-institutional study led by the Icahn School of Medicine at Mount Sinai reports one-third of patients with relapsed or refractory multiple myeloma remained in remission for at least

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New standard of care emerges for multiple myeloma

May 30, 2025  The GIST New standard of care emerges for multiple myeloma by Charlotte Schubert, University of Miami Leonard M. Miller School of Medicine edited by Sadie Harley, reviewed by Andrew Zinin   Micrograph of a plasmacytoma, the histologic correlate of multiple myeloma. H&E stain. Credit: Wikipedia/CC BY-SA 3.0 A new four-drug combination is highly effective and

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