myelin damage

Enzyme linked to myelin damage may hold key to neurodegenerative diseases

by Erik Robinson, Oregon Health & Science University edited by Stephanie Baum, reviewed by Robert Egan  Editors’ notes Immunostaining using a CEMIP antibody (purple) and in situ hybridization using a CEMIP probe (using RNAScope; red) reveal co-localization of both signals in sections of lumbar spinal cords from mice with EAE at 15 days post-inoculation. Scale bar = 50 µm. Nuclei […]

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Highly sensitive imaging technique detects myelin damage

by Boston University School of Medicine edited by Gaby Clark, reviewed by Robert Egan  Editors’ notes (a) Widefield 4× tile scan of a coronal brain slice from a rhesus monkey with an induced cortical lesion (yellow arrow). qBRM RGB parameter maps are rendered where the brightness of each pixel maps the retardance (myelin density), and the optic-axis orientation (related

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