metabolism

Novel antibody targets fat cell protein, offering new approach to treating metabolism-related liver cancer

by Hong Kong Polytechnic University edited by Gaby Clark, reviewed by Robert Egan  Editors’ notes  The GIST Add as preferred source Graphical abstract. Credit: Journal of Clinical Investigation (2025). DOI: 10.1172/jci182322 Liver cancer is one of the three deadliest cancers worldwide, and metabolic dysfunction-related cases have become increasingly common in recent years. A research team from The Hong Kong Polytechnic […]

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The ‘yo-yo effect’ impairs metabolism and reduces brown fat activity in women

by Fernanda Bassette, FAPESP edited by Gaby Clark, reviewed by Robert Egan  Editors’ notes  The GIST Add as preferred source An infrared thermography camera captured the increase in temperature in the supraclavicular region, which indicates greater BAT activity. Credit: Laura Ramos Gonçalves Gomes/FCA-UNICAMP A study conducted by researchers at the State University of Campinas (UNICAMP) in São Paulo,

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How diet affects aging metabolism differently for men and women

By Dr. Liji Thomas, MDReviewed by Lauren HardakerNov 7 2025 Researchers have uncovered striking sex-based differences in how diet influences metabolism with age, revealing that plant proteins and whole grains enhance men’s insulin sensitivity, while moderate wine consumption benefits women. Study: Sex Differences in Associations Between Diet and Metabolic Health in Older Adults: The Roles of Vegetable Protein

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Newly discovered gut bacteria proteins influence hormones, metabolism and bone density

by University of Copenhagen edited by Sadie Harley, reviewed by Robert Egan Credit: CC0 Public Domain The intestines are home to trillions of microorganisms that produce substances capable of regulating all the body’s organs via the bloodstream and the gut’s nervous system. Yet, only little is known about the effects of most of the bacteria that make up

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Can Blocking AMH Reverse PCOS? New Study Says Yes – endocrinology & metabolism

Researchers from the French National Institute of Health & Medical Research (Inserm), University of Lille in Lille, France, and the university’s teaching hospital CHU de Lille have identified a promising new therapeutic strategy for polycystic ovary syndrome (PCOS). In preclinical models, the use of antibodies that block the activity of anti-Müllerian hormone (AMH) helped prevent

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‎Mapping the metabolism of blood stem cells

Scientists mapping how nutrients and lipids shape bone marrow blood stem cells from health to aging and leukemia Peer-Reviewed Publication Max Planck Institute of Immunobiology and Epigenetics FacebookXLinkedInWeChatBlueskyMessageWhatsAppEmail image: Comprehensive analysis of blood stem cells: Using advanced FACS sorting and innovative low-input methods, blood stem cells (HSPCs) and their progenitors were isolated from human bone

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Antibody sIgM emerges as a key guardian of gut health and metabolism

by Martin J. Hackett, University of Pennsylvania edited by Lisa Lock, reviewed by Robert Egan Gut tissue damage induced by the lack of sIgM: Representative hematoxylin and eosin staining of gut paraffin sections from fish lacking IgM (IgM-depleted) or with physiological IgM levels (control fish). Extensive tissue damage is shown within the green circled tissue areas which indicate

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