metabolic diseases

Aged blood vessel cells drive metabolic diseases

Cedars-Sinai preclinical study lays foundation for future development of treatments for complex diseases like diabetes Peer-Reviewed Publication Cedars-Sinai Medical Center Investigators from the Center for Advanced Gerotherapeutics at Cedars-Sinai found that aged blood vessel cells play a key role in the development of metabolic disorders, including diabetes. The preclinical findings, published in Cell Metabolism, could lead […]

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‘Switching off’ enzyme prevents diet-induced obesity, other metabolic diseases

by Monash University edited by Lisa Lock, reviewed by Andrew Zinin  Editors’ notes Camkk2MKO mice are protected from HFD-induced hepatic steatosis. Credit: Molecular Metabolism (2025). DOI: 10.1016/j.molmet.2025.102250 An international team led by Monash University and Baylor College of Medicine, Texas, has found “switching off” an enzyme called CaMKK2 in immune cells that drive inflammation prevents diet-induced obesity, diabetes and fatty liver

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