lynch syndrome

Urine DNA test may spot Lynch syndrome urinary cancers before symptoms

by Newcastle University edited by Lisa Lock, reviewed by Andrew Zinin  Editors’ notes  The GIST Add as preferred source Initial urine MSI analysis results from 81 individuals with a diagnosis of MSH2-Lynch syndrome (A) and a timeline of urine and tumor MSI analysis results for participants with an MSI-High urine result (B). Credit: eBioMedicine (2025). DOI: 10.1016/j.ebiom.2025.105969 A pioneering genetic […]

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Immune-targeting vaccine shows promise intercepting cancer in patients with Lynch Syndrome

by University of Texas MD Anderson Cancer Center edited by Gaby Clark, reviewed by Andrew Zinin  Editors’ notes  The GIST Add as preferred source Immunogenic FSPs are present in cancer and precancer lesions of LS carriers from an independent cohort. Credit: Nature Medicine (2026). DOI: 10.1038/s41591-025-04182-9 The investigational cancer vaccine, NOUS-209, was found to safely stimulate the immune system to

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