lung scarring

by University of California, San Francisco edited by Sadie Harley, reviewed by Andrew Zinin  Editors’ notes A) Model of IRE1α control of AT2 plasticity and promotion of fibrosis by RIDD and downregulation of Fgfr2. B) Model of IRE1α modulation of Fgf signaling and potential effects in other epithelial tissues. Credit: Journal of Clinical Investigation (2025). DOI: 10.1172/jci184522 Pulmonary fibrosis is […]

by University of Virginia edited by Gaby Clark, reviewed by Robert Egan  Editors’ notes Immunohistochemistry staining of JAML (junctional adhesion molecule-like) in idiopathic pulmonary fibrosis lung tissue at (A) 123, (B) 403, and (C) 4003 magnification. GCHFR (GTP cyclohydrolase 1 feedback regulator) immunostaining of idiopathic pulmonary fibrosis lung tissue at (D) 123, (E) 403, and (F) 4003 magnification.

by Kyle Marr, University of Calgary edited by Stephanie Baum, reviewed by Robert Egan Credit: Immunity (2025). DOI: 10.1016/j.immuni.2025.05.002 Researchers at the University of Calgary studying a lethal lung disease called pulmonary fibrosis have found that neurons known to help detect pain are also critical for reducing harmful lung inflammation that leads to the disease. Pulmonary fibrosis, also called lung