immune response

Astrocytes found to aid spinal cord repair by signaling immune response

by Cedars-Sinai Medical Center edited by Sadie Harley, reviewed by Robert Egan  Editors’ notes Credit: Pixabay/CC0 Public Domain Cedars-Sinai investigators have discovered a healing mechanism that could one day be harnessed to help treat patients with spinal cord injuries, stroke, and neurological conditions such as multiple sclerosis. Their study, published in Nature, describes a previously unknown function of astrocytes, […]

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A toast to BRD4: How acidity changes the immune response

by Linsey Covino-Deaso, Children’s Hospital Boston edited by Lisa Lock, reviewed by Robert Egan  Editors’ notes Credit: Cell (2025). DOI: 10.1016/j.cell.2025.06.033 It started with wine. Or more precisely, a conversation about it. “My colleagues and I were talking about how some people think drinking wine may be anti-inflammatory,” recalls Xu Zhou, Ph.D., from the Division of Gastroenterology, Hepatology, and Nutrition

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Study uncovers key RNA-driven network behind colorectal cancer progression and immune response

by Zhang Nannan, Chinese Academy of Sciences edited by Lisa Lock, reviewed by Robert Egan   A proposed model suggests that lncRNA 60967.1 plays a regulatory role in modulating the PLCD4/ATRA axis and anti-PD-1 therapy, influencing immune responses and affecting CRC progression. Credit: Molecular Cancer (2025). DOI: 10.1186/s12943-025-02359-x A research team led by Prof. Gu Hongcang and Zhang Fan from

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Study shows loss of Y in blood cells hinders immune response to cancer

by University of Arizona edited by Sadie Harley, reviewed by Robert Egan   Credit: Pixabay/CC0 Public Domain A study initiated by a University of Arizona Comprehensive Cancer Center physician-scientist defined for the first time how loss of the Y chromosome in male immune cells negatively affects immune system function, which may explain why loss of Y is associated

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