glioblastoma

by Brown University edited by Sadie Harley, reviewed by Robert Egan  Editors’ notes  The GIST Add as preferred source Graphical abstract. Credit: Cell Reports (2025). DOI: 10.1016/j.celrep.2025.116516 A study by Brown University Health researchers has identified a crucial factor that may help improve treatment for glioblastoma, one of the most aggressive and common forms of adult brain cancer. The findings, […]

Peer-Reviewed Publication InSilico Medicine image: Evaluation of (Z)-endoxifen as a potential therapy for glioblastoma multiforme through computational and experimental analyses view more   Credit: Insilico Medicine Cambridge, MA — 12/02/2025 — Insilico Medicine (“Insilico”), a global leader in AI-powered drug discovery, and Atossa Therapeutics (“Atossa”) (Nasdaq: ATOS), a clinical-stage biopharmaceutical company developing novel treatments for breast cancer

by Albert Einstein College of Medicine edited by Sadie Harley, reviewed by Robert Egan  Editors’ notes A case of glioblastoma relapsed during immunotherapy. Credit: Yan Li et al, CC BY 4.0 Scientists at Montefiore Einstein Comprehensive Cancer Center (MECCC) and Albert Einstein College of Medicine have shown for the first time that glioblastoma—the deadliest form of brain cancer—affects not

Researchers have identified a previously unknown determinant of resistance to immune checkpoint blockers in glioblastoma and a strategy to overcome it. Peer-Reviewed Publication Massachusetts General Hospital Rakesh Jain, PhD, director of the Edwin Steele Laboratories for Tumor Biology in the Department of Radiation Oncology at Massachusetts General Hospital and Andrew Werk Professor of Radiation Oncology at Harvard Medical School,

by ITER edited by Stephanie Baum, reviewed by Robert Egan   The fusion superkine (FSK) stimulated higher tumor regression and enhanced survival in vivo more than the individual superkine (IL-24S) or cytokine (IL-15) in glioblastoma cancer models. In addition, killing of GBM cells was induced, as well as increased tumor infiltration of T cells, dendritic cells (DCs), macrophages