Discovery of Gpr45 gene activity in brain cilia sheds light on genetic roots of overeating

by UT Southwestern Medical Center edited by Gaby Clark, reviewed by Robert Egan   GPR45 transports Gαs into primary cilia to regulate food intake. Credit: Science (2025). DOI: 10.1126/science.adp3989 Using a tool called Automated Meiotic Mapping (AMM) that was developed at UT Southwestern Medical Center, a team of researchers has identified a gene that appears to be key to regulating food intake. […]

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