Computational deep dive reveals hidden cancer drug targets and repurposing opportunities
by Sanford-Burnham Prebys edited by Gaby Clark, reviewed by Robert Egan Editors’ notes DeepTarget’s predictions are based on the principle that removing a gene encoding the protein target of a given drug through CRISPR-Cas9 gene editing can mimic the inhibitory effects of that drug. The tool was built by leveraging large-scale genetic and drug screening experiments with comprehensive […]
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