breast cancer

Could reducing inflammation help combat fatigue in people with early-stage breast cancer?

by Wiley edited by Sadie Harley, reviewed by Robert Egan  Editors’ notes Credit: Anna Tarazevich from Pexels New research reveals that inflammatory responses may play a role in different types of fatigue experienced by many people with cancer. The findings are published in Cancer. Cancer-related fatigue can be a distressing and persistent burden that causes patients to feel physical, […]

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Restoring order to dividing cancer cells may halt triple negative breast cancer spread

by Weill Cornell Medical College edited by Andrew Zinin  Editors’ notes Left: Normal cell division with the chromosomes (blue) lined up and ready to be pulled into two separate daughter cells by the two centrosomes (green). Right: In faulty cell division, too many centrosomes are present, resulting in multiple cells with chromosomal instability. Credit: Dr. Shelly Yang

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Metabolic markers may predict breast cancer in high-risk women

by Columbia University’s Mailman School of Public Health edited by Gaby Clark, reviewed by Andrew Zinin  Editors’ notes Volcano plot of metabolites/features. Credit: Breast Cancer Research (2024). DOI: 10.1186/s13058-024-01896-5 Breast cancer remains the most common cancer and the leading cause of cancer-related death among women worldwide, with incidence rates continuing to rise. However, known risk factors, including genetics and lifestyle,

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Pioneering strategy may keep breast cancer from coming back

by Perelman School of Medicine at the University of Pennsylvania edited by Sadie Harley, reviewed by Robert Egan   Credit: Unsplash/CC0 Public Domain A first-of-its-kind clinical trial has shown it’s possible to identify breast cancer survivors who are at higher risk of their cancer coming back due to the presence of dormant cancer cells and to effectively treat

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Study finds type 2 diabetes blood factors drive breast cancer aggression

by Boston University School of Medicine edited by Sadie Harley, reviewed by Robert Egan   Illustration of scRNAseq workflow in PDO model of breast cancer TME. Credit: Communications Biology (2025). DOI: 10.1038/s42003-025-08663-y People with type 2 obesity-driven diabetes tend to have more aggressive breast cancers, but no one knows exactly why. A new study by researchers at Boston University Chobanian

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Study uncovers how beta blockers could halt the progression of triple negative breast cancer

by Monash University edited by Sadie Harley, reviewed by Andrew Zinin Credit: Unsplash/CC0 Public Domain Monash University researchers have identified a molecular biomarker in triple negative breast cancer (TNBC) tumors which could inform when beta blockers can play a role in “switching off” tumor progression. When stress hormones are released by the body’s nervous system, they can activate a receptor

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Researchers uncover potential mechanism driving treatment resistance in common breast cancer

by Garvan Institute of Medical Research edited by Sadie Harley, reviewed by Andrew Zinin Breast cancer cells in their ‘sleeping’ state (senescence) after treatment. When the JNK pathway is disrupted, cancer cells are less likely to enter this state and instead continue dividing, leading to therapy resistance. Credit: Garvan Institute A team of scientists at the Garvan Institute

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Scientists reverse immunotherapy-resistance by suppressing EPIC1 in mouse model of breast cancer

by Krystal Kasal, Phys.org edited by Gaby Clark, reviewed by Robert Egan EPIC1 reduces dsRNA biogenesis. Credit: Science Signaling (2025). DOI: 10.1126/scisignal.adr9131 Immunotherapy employs patients’ own immune systems to fight cancer, and it has shown itself to be an effective treatment in many cases. However, some cancers, like triple-negative breast cancer (TNBC), show resistance to immunotherapy. This occurs when tumor

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Study links persistent fatigue in breast cancer survivors to increased inflammation

by Ali Weinstein, George Mason University edited by Sadie Harley, reviewed by Andrew Zinin   Credit: Miguel Á. Padriñán from Pexels For many breast cancer survivors, fatigue may linger long after treatment ends, which can have a significant impact on cognitive function, ability to work, and overall quality of life. A new study from George Mason University’s College

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A saliva-based test for breast cancer might be near

by Ernie Mundell edited by Gaby Clark, reviewed by Andrew Zinin In a small new study, a handheld saliva-sampling device successfully detected breast cancer 100% of the time, researchers said. The study only involved 29 saliva samples, and more research is needed. However, the results remain “very exciting because this device could improve access to breast cancer screening and

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