b cells

B cells temporarily regain stem-like flexibility, increasing risk of lymphoma formation

by Weill Cornell Medical College edited by Stephanie Baum, reviewed by Andrew Zinin  Editors’ notes The illustration depicts how, during differentiation, cells normally lose their plasticity and ability to acquire new fates. However, when fully differentiated B cells (naive B cells) initiate an immune response called the germinal center reaction, they transiently regain plasticity under the control of […]

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T-bet protein found essential for maintaining flu-fighting memory B cells

by Jeff Hansen, University of Alabama at Birmingham edited by Andrew Zinin Credit: Pixabay/CC0 Public Domain At the surface, the immune response to a flu virus is simple. Some cells recognize the pathogen and send a signal to the immune system, and immune cells produce a potentially lifesaving antibody against the virus. Antigen in, antibody out. However,

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