alzheimer treatment

‎The good side of a side effect: Brain swelling during Alzheimer’s treatment may signal strong response

by Houston Methodist edited by Lisa Lock, reviewed by Robert Egan  Editors’ notes  The GIST Add as preferred source MRI and Aβ PET findings in patients 1 and 4. In both patients, the regions of ARIA-E on MRI correspond to the regions of greatest decrease in Aβ-PET signal after lecanemab therapy (arrows). Credit: American Journal of Neuroradiology (2025). DOI: 10.3174/ajnr.a9111 […]

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Novel discovery reveals how brain protein OTULIN controls tau expression and could transform Alzheimer’s treatment

Groundbreaking research identifies unexpected role for deubiquitinase enzyme in regulating toxic tau protein accumulation Peer-Reviewed Publication Genomic Press image: The working model shows the known and novel functions of OTULIN. OTULIN regulates proteostasis, cell death, inflammation, and cell survival/development. The novel non-canonical function identified in this study demonstrates OTULIN role as a regulator of RNA

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