alzheimer disease

by University of Oslo edited by Stephanie Baum, reviewed by Robert Egan  Editors’ notes NR induces transcription of genes involved in axon development, oxygen metabolism, mitochondrion localization, and autophagy in tauopathy mice. GO terms enriched in each of the eight classes of clusters in (A); each circular bar graph represents one cluster or class of clusters, and bar […]

by Tokyo Metropolitan University edited by Sadie Harley, reviewed by Robert Egan  Editors’ notes Tau protein fibrillization mirrors polymer crystallization. The pathway taken as tau proteins form fibrils is very similar to the pathway taken by polymers as they crystallize. Credit: Tokyo Metropolitan University Researchers from Tokyo Metropolitan University have applied ideas from polymer physics to illuminate the

by University of Oslo edited by Stephanie Baum, reviewed by Robert Egan  Editors’ notes NR induces transcription of genes involved in axon development, oxygen metabolism, mitochondrion localization, and autophagy in tauopathy mice. GO terms enriched in each of the eight classes of clusters in (A); each circular bar graph represents one cluster or class of clusters, and bar

by Krystal Kasal, Phys.org edited by Gaby Clark, reviewed by Robert Egan  Editors’ notes Neuronal nanotubes mediate intercellular transport and disease. Credit: Science (2025). DOI: 10.1126/science.adr7403 Neurons in the brain communicate with each other through synapses—connection points that allow the passage of electrical and chemical signals. In non-neuronal cells, direct cell-to-cell connections have been found to occur with the assistance

by University of Liverpool edited by Lisa Lock, reviewed by Robert Egan  Editors’ notes An overview of the biosensing system. Credit: Advanced Healthcare Materials (2025). DOI: 10.1002/adhm.202503155 Scientists at the University of Liverpool have developed a new low-cost blood test that could make it easier to detect Alzheimer’s disease at an earlier stage—helping patients receive treatment and support sooner. Two

by Texas Tech University edited by Gaby Clark, reviewed by Robert Egan  Editors’ notes The LMD6 laser microdissection system was used to selectively isolate distinct regions within the brain hemispheres of young and aged Tg2576 AD mice following Amytracker 680 injection. Credit: Fluids and Barriers of the CNS (2025). DOI: 10.1186/s12987-025-00685-2 A team of scientists at Texas Tech University Health

Scientists analyze decades of research, showing how immune cells shape the burden of Alzheimer’s disease Peer-Reviewed Publication Chinese Medical Journals Publishing House Co., Ltd. image: A comparison between a healthy brain (left) and a brain severely affected by Alzheimer’s disease (right). Alzheimer’s leads to significant shrinkage and loss of brain tissue, reflecting the damage caused

by American Neurological Association edited by Gaby Clark, reviewed by Robert Egan Credit: Polina Tankilevitch from Pexels The timing of hormone replacement therapy may make a big difference in a woman’s risk of developing Alzheimer’s disease. Starting treatment within five years of menopause may lower the risk by as much as 32%, but delaying it until 65

Peer-Reviewed Publication University of Michigan Some regions of the brain in people with Alzheimer’s reorganize more often while at rest than in people without the disease––and in healthy people this frequent reshuffling sometimes predicts who will develop the condition later, according to a new study from the University of Michigan and Columbia University. The brain’s