Targeting epigenetic modifiers and splicing regulators together may offer new acute myeloid leukemia treatment paths
by Sylvester Comprehensive Cancer Center edited by Sadie Harley, reviewed by Robert Egan Editors’ notes Graphical summary of the results of our whole study. Credit: Science Advances (2026). DOI: 10.1126/sciadv.adu8292 Treating acute myeloid leukemia (AML) depends on knowing what goes wrong inside cells. A new study suggests that two genetic mutations—IDH2 and SRSF2—work cooperatively to mis-splice RNA messages and change […]
