Neurology

New treatment could reduce brain damage from stroke, study in mice shows

July 31, 2025 / Neurology, Research update / InnovateMed Author / brain damage

by University of Cambridge edited by Sadie Harley, reviewed by Andrew Zinin Graphical abstract. Credit: Cardiovascular Research (2025). DOI: 10.1093/cvr/cvaf118 Cambridge scientists have developed and tested a new drug in mice that has the potential to reduce damage to the brain when blood flow is restored following a stroke. The study, “Local arterial administration of acidified malonate as an adjunct therapy […]

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Critical brain link could explain how Alzheimer’s disease takes hold –

July 28, 2025 / Alzheimer's disease, Neurology, Research update / InnovateMed Author / alzheimer

A crucial link between the brain’s cleaning system and deterioration of neurons associated with Alzheimer’s disease has been discovered by University of Queensland researchers. Alzheimer’s disease – illustrative photo. Image credit: Pixabay (Free Pixabay license) Professor Elizabeth Coulson, from UQ’s School of Biomedical Sciences and Queensland Brain Institute, said the research has revealed a direct link between early brain degeneration

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New brain pathway discovered as key to memory formation

July 28, 2025 / Neurology, Research update / InnovateMed Author / brain pathway

Posted Today University of Queensland researchers have discovered a new lipid-based pathway essential for memory formation – a breakthrough that could lead to treatments for post-traumatic stress disorder (PTSD). Mental Health – illustrative photo. Image credit: Pixabay (Free Pixabay license) University of Queensland researchers have discovered a new lipid-based pathway essential for memory formation – a breakthrough that

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Study shows how brain-to-computer ‘electroceuticals’ can help restore cognition

July 11, 2025 / Neurology, Research update / InnovateMed Author / electroceuticals

by Vanderbilt University edited by Lisa Lock, reviewed by Andrew Zinin Credit: Neuron (2025). DOI: 10.1016/j.neuron.2025.05.018 Research led by Thilo Womelsdorf, professor of psychology and biomedical engineering at the Vanderbilt Brain Institute, could revolutionize how brain-computer interfaces are used to treat disorders of memory and cognition. The study, “Adaptive reinforcement learning is causally supported by anterior cingulate cortex and striatum,” was published June

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Nerve pain drug gabapentin linked to increased dementia, cognitive impairment risks

July 11, 2025 / Clinical Practice, Dementia, Neurology / InnovateMed Author / nerve pain drug

by British Medical Journal edited by Sadie Harley, reviewed by Robert Egan Credit: Pixabay/CC0 Public Domain Receiving six or more prescriptions of the drug gabapentin for low back pain is associated with significantly increased risks of developing dementia and mild cognitive impairment (MCI)—29% and 85%, respectively—finds a large medical records study published online in the journal Regional

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‘Dimmer switch’ drug candidates offer hope for safer nerve pain and ischemic disease treatments

July 9, 2025 / Neurology, Research update / InnovateMed Author / ischemic disease treatment, nerve pain

by Monash University edited by Sadie Harley, reviewed by Robert Egan Cryo-EM structure of the human adenosine A1 receptor (A1R, white) in complex with the orthosteric agonist adenosine (magenta) and the allosteric modulator MIPS521 (cyan). Credit: Dr. Anh T.N. Nguyen, Monash University Scientists have discovered novel drug candidates which could ultimately lead to new effective treatments for conditions

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Dementia protection linked to where the body lies—belly fat a risk factor

July 8, 2025 / Dementia, Neurology, Patient education / InnovateMed Author / belly fat, dementia

by Monash University edited by Lisa Lock, reviewed by Andrew Zinin Credit: World Obesity Federation Men with high levels of belly fat are at increased risk of dementia, according to a new study by Monash University researchers of more than 17,000 individuals aged 65 to 98 years in the ASPREE Study. Importantly, the study also found that

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A signal that never repeats—how the brain creates bookmarks to map time

July 7, 2025 / Alzheimer's disease, Neurology, Research update / InnovateMed Author / Brain Mapping

by Rita Elmkvist Nilsen, Norwegian University of Science and Technology edited by Lisa Lock, reviewed by Robert Egan Neural population activity in the LEC organizes events in time. Credit: Science (2025). DOI: 10.1126/science.adr0927 The brain doesn’t merely register time—it structures it, according to new research from the Kavli Institute for Systems Neuroscience published in Science. The research team led by NTNU’s Nobel

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Early mitochondrial impairment and myelin loss tied to multiple sclerosis brain damage

June 17, 2025 / Neurology, Research update / InnovateMed Author / mitochondrial impairment, multiple sclerosis brain damage

by University of California – Riverside edited by Robert Egan, reviewed by Andrew Zinin Editors’ notes Credit: Pixabay/CC0 Public Domain Multiple sclerosis (MS) affects an estimated 2.3 million people worldwide. Approximately 80% of people with MS have inflammation in the cerebellum, the part of the brain that helps control movement and balance, potentially leading to tremors, poor coordination,

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Scientists can now target the cells at the center of ALS

June 17, 2025 / Neurology, Research update / InnovateMed Author / Amyotrophic Lateral Sclerosis

Allen Institute June 16, 2025 ALS is a cruel disease. It robs the body of its ability to control itself—the ability to move, the ability to communicate. While there are currently no effective treatments to reverse its debilitating symptoms, Allen Institute researchers have opened a window of hope. For the first time ever, scientists have

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