Cancer

Tumor allies or foes? Unraveling neutrophil roles in cancer

Peer-Reviewed Publication China Anti-Cancer Association image: Potential pro- and anti-tumor functions of tumor-associated neutrophils (TANs). TANs may either promote or inhibit tumorigenesis and tumor progression through various immune mechanisms. (Figure left) Anti-tumor roles of TANs, which involve direct tumor cytotoxicity through secretion of protease granules, like reactive oxygen species (ROS) and myeloperoxidase (MPO). Additionally, TANs […]

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Insights into palliative care for patients with cancer

by Mass General Brigham edited by Sadie Harley, reviewed by Andrew Zinin Credit: Ivan Samkov from Pexels For patients with a cancer diagnosis, early specialty palliative care is considered the standard of care. However, many patients with advanced cancer do not consistently receive specialty palliative care, especially during the early stages of their illness. Isaac Chua, MD, MPH,

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Beyond the Binary: Integrating CAR T and Bispecific Antibodies in Multiple Myeloma Treatment – cancer

MILAN — The treatment landscape for relapsed and refractory multiple myeloma (RRMM) has shifted dramatically with the emergence of immunotherapies such as chimeric antigen receptor (CAR) T-cell therapies and bispecific antibodies (bsAbs). These novel approaches have delivered unprecedented outcomes in heavily pretreated patients. Yet determining the optimal treatment strategy remains a clinical challenge. Here at the 2025

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Liver drives cancer cachexia through systemic signaling response, study finds

by Verena Schulz, Helmholtz Association of German Research Centres edited by Gaby Clark, reviewed by Andrew Zinin  Graphical abstract. Credit: Cell (2025). DOI: 10.1016/j.cell.2025.06.039 Many people with cancer experience dramatic loss of muscle and fat tissue. In many cases, even the heart muscle is affected, which further weakens the body. This wasting syndrome, known as cachexia, affects around half of

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New diagnostic breakthrough predicts which head and neck cancer patients can be cured with surgery alone

by University of Turku edited by Lisa Lock, reviewed by Andrew Zinin Credit: EMBO Molecular Medicine (2025). DOI: 10.1038/s44321-025-00266-8 Researchers from the University of Turku and Turku University Hospital, Finland, led by Docent Sami Ventelä and Professor Jukka Westermarck, have developed a diagnostic tool that can revolutionize the treatment guidance of head and neck squamous cell carcinoma. Their study, recently published in EMBO

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Stevia leaf extract has potential as anticancer treatment, researchers find

by Hiroshima University edited by Gaby Clark, reviewed by Andrew Zinin The overall mechanism for the induction of apoptosis in PANC-1 cells by stevia leaf extract fermented with Lactobacillus plantarum SN13T strain. Credit: Zhang Rentao/Hiroshima University Stevia may provide more benefits than as a zero-calorie sugar substitute. When fermented with bacteria isolated from banana leaves, stevia extract kills off

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Cancer drug shows promise as treatment for blindness

by Agency for Science, Technology and Research (A*STAR), Singapore edited by Sadie Harley, reviewed by Andrew Zinin PRL3 (but not PRL1) is associated with embryonic angiogenesis and blood vessels in PRL3+ tumors have reduced pericyte coverage compared to those in PRL3- tumors. Credit: Nature Communications (2025). DOI: 10.1038/s41467-025-59929-2 Singapore researchers have discovered that a new cancer drug, originally developed at A*STAR Institute

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Why are colorectal, other GI cancers on the rise in younger people?

Written by Katharine Lang on July 9, 2025 — Fact checked by Jill Seladi-Schulman, Ph.D.   Colorectal and other gastrointestinal cancers are on the rise in younger people. The question is: why? Image credit: SolStock/Getty Images. Increasing age is the greatest risk factor for all types of cancer, with most cases being diagnosed in people

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Modified Herpes Virus Found to Shrink Deadly Skin Cancers in Clinical Trial

Health 10 July 2025 By Carly Cassella Melanoma tumor. (saruservice/iStock/Getty Images Plus) Scientists have hijacked the herpes virus and turned it into a cancer-busting ally. A decade after the United States Food and Drug Administration (FDA) approved the first virus-based cancer therapy, another potentially life-saving treatment is on the horizon. A genetically modified herpes simplex virus, called RP1, has

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New research offers reassurance about localized prostate cancer prognosis

by National Comprehensive Cancer Network edited by Sadie Harley, reviewed by Robert Egan Credit: Unsplash/CC0 Public Domain New research in JNCCN—Journal of the National Comprehensive Cancer Network finds that for people diagnosed with nonmetastatic low-risk prostate cancer later in life, and treated according to NCCN Clinical Practice Guidelines in Oncology (NCCN Guidelines), 90% were likely to survive their cancer

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