Cancer

Higher lifetime alcohol consumption linked to colorectal cancer risk

by Wiley edited by Sadie Harley, reviewed by Robert Egan  Editors’ notes  The GIST Add as preferred source Credit: Unsplash/CC0 Public Domain Studies have demonstrated a link between alcohol consumption and an elevated risk of colorectal cancer. New research now reveals that higher lifetime alcohol consumption is also associated with a higher risk, especially for rectal cancer, and […]

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Discovery illuminates how inflammatory bowel disease promotes colorectal cancer

by Weill Cornell Medical College edited by Lisa Lock, reviewed by Robert Egan  Editors’ notes  The GIST Add as preferred source Enhanced image showing where genes are active in colon tissue, revealing neutrophils located close to pre-cancerous epithelial cells. Credit: Longman lab. A chain of immune reactions in the gut—driven by a key signaling protein and a surge of

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Inflammatory pathway reveals targetable weakness in hard-to-treat blood cancer

by Indiana University edited by Robert Egan  Editors’ notes  The GIST Add as preferred source Kate Ho is working in the lab. Credit: Indiana University New research co-led by Indiana University School of Medicine scientists has exposed a vulnerability in acute myeloid leukemia by identifying the blood cancer’s reliance on a specific signaling pathway involved in the

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Most elderly cancer patients receive inappropriate drugs until final months, study finds

by University of Tsukuba edited by Sadie Harley, reviewed by Robert Egan  Editors’ notes  The GIST Add as preferred source Credit: Unsplash/CC0 Public Domain Analysis of the medical records of 1,269 elderly patients with advanced cancer by researchers at the University of Tsukuba has found that more than 70% were prescribed potentially inappropriate medications (PIMs) and that the

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Predicting prostate cancer recurrence through power of AI

edited by Sadie Harley, reviewed by Andrew Zinin  Editors’ notes  The GIST Add as preferred source Credit: Unsplash/CC0 Public Domain To help meet the potentially complex needs of patients after prostate cancer treatment and offer the precision and care necessary in the follow-up journey, Mayo Clinic’s Department of Radiation Oncology developed the PSA Control Tower. This is

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Study Adds Evidence That Nicotinamide Prevents Skin Cancers

Richard Mark Kirkner September 22, 2025 A large retrospective study of Veterans Affairs patients with a history of skin cancer has provided support to what a smaller randomized clinical trial reported about a decade ago: that patients taking nicotinamide 500 mg twice daily can significantly reduce their risk for skin cancer, with the greatest effect

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Colorectal cancer’s immune puzzle cracked: Two Treg cell types shape survival odds

by Ian Demsky, Memorial Sloan Kettering Cancer Center edited by Sadie Harley, reviewed by Andrew Zinin  Editors’ notes Credit: Unsplash/CC0 Public Domain In most solid tumors, high numbers of regulatory T (Treg) cells are associated with poorer outcomes because they dampen the immune system’s ability to fight against a tumor. Colorectal cancer, however, is a puzzling exception. A

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Clinical trial of personalized cancer vaccine demonstrates feasibility, safety, immune activation

by Harvard University edited by Gaby Clark, reviewed by Robert Egan The personalized biomaterial-based cancer vaccine consists of a porous biomaterial scaffold the size of an aspirin tablet that is infused with immune cell-recruiting and activating molecules and inactivated tumor antigens derived from tumors of the trial participants. Credit: Wyss Institute at Harvard University The first-in-human clinical phase

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AI can help cancer patients better understand CT reports

by Paul Hellmich, Technical University Munich edited by Sadie Harley, reviewed by Robert Egan  Editors’ notes Credit: CC0 Public Domain Medical reports written in technical terminology can pose challenges for patients. A team at the Technical University of Munich (TUM) has investigated how artificial intelligence can make CT findings easier to understand. In the study, reading time decreased,

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New therapeutic strategies show promise against a hard-to-treat prostate cancer

by McGill University edited by Gaby Clark, reviewed by Andrew Zinin  Editors’ notes Credit: cottonbro studio from Pexels A new study has uncovered promising therapeutic strategies against one of the deadliest forms of prostate cancer. McGill University researchers at the Rosalind and Morris Goodman Cancer Institute (GCI) identified a mechanism driving neuroendocrine prostate cancer, a rare and highly

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