March 6, 2026

New Oral GLP-1 Beats Oral Semaglutide for A1c, Weight Loss

March 6, 2026 / Research update / InnovateMed Author / oral GLP1

Orforglipron, a novel oral nonpeptide GLP-1 receptor agonist (RA), led to a greater reduction in A1c and more significant weight loss compared to oral semaglutide in patients with type 2 diabetes (T2D) inadequately controlled by metformin, a phase 3 randomized controlled trial showed. “The primary objective of non-inferiority was met, and both orforglipron doses showed superiority to both semaglutide doses,” lead author […]

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Tracing extracellular vesicles’ journey from cancer cells to urine

March 6, 2026 / Research update / InnovateMed Author / cancer

by Institute of Science Tokyo edited by Gaby Clark, reviewed by Robert Egan Editors’ notes The GIST Add as preferred source This study tracked the journey of small extracellular vesicles from distant tumor cells to urine and revealed new insights into how kidney cells process them. The results pave the way for better cancer diagnostics by leveraging liquid

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Evo 2: The AI That Learned to Read DNA Across All Life on Earth — And It’s Already Finding Things We Missed – genetics

March 6, 2026 / Research update / InnovateMed Author / Evo 2

Evo 2 is an open-source artificial intelligence trained on 8.8 trillion base pairs of DNA from bacteria, archaea, and eukaryotes — essentially every major branch of life. A DNA strand – artistic impression. Image credit: Alius Noreika / AI Key Takeaways: Evo 2 was trained on 8.8 trillion bases from all three domains of life plus bacterial

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The impact of Trump’s ‘Don’t take Tylenol’

March 6, 2026 / News update / InnovateMed Author / tylenol

Acetaminophen use in emergency departments for pregnant women plummeted in the wake of last year’s press conference in which President Trump and his health officials cautioned against the use of the drug, according to a new study published yesterday. Health officials said taking the painkiller increased the risk of having a kid with autism, even though the

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Using Machine Learning to Develop Personalized Vaccines for Cancer

March 6, 2026 / Research update / InnovateMed Author / cancer

Yale researchers have developed a machine learning model, called Immunostruct, that can help scientists create more personalized vaccines, including cancer vaccines. They described the tool in Nature Machine Intelligence along with findings from applying it to cancer and immunology data. Blood samples – illustrative photo. Image credit: Karolina Kaboompics via Pexels, free license When a potential threat, such as

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Platform to map living brain noninvasively takes next big step – synthetic biology

March 6, 2026 / Research update / InnovateMed Author / living brain

Gene therapy has been successfully used to treat a number of diseases, including immune deficiencies, hereditary blindness, hemophilia and, recently, Huntington’s disease, a fatal neurological disorder. RMAs, the synthetic serum markers, expressed in striatal neurons. Image credit: Costa lab at Emory University An advance reported in the journal Neuron adds to the technique’s growing track record of

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Study reveals how gut bacteria and diet can reprogram fat to burn more energy

March 6, 2026 / Clinical Practice / InnovateMed Author / gut bacteria

Findings published in Nature uncover a microbiome-driven pathway that turns energy storing fat into calorie burning fat in mice Peer-Reviewed PublicationCity of Hope image: Scientists at City of Hope, the Broad Institute and Keio University have discovered how specific gut bacteria work together with diet to flip a metabolic switch — transforming energy‑storing white fat

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What to know about the virus with no vaccine, treatment hitting certain states

March 6, 2026 / Clinical Practice / InnovateMed Author / virus

Sara Moniuszko USA TODAY Updated March 5, 2026, 4:02 p.m. ET Cases of human metapneumovirus, or HMPV, are hitting certain states, including California and New Jersey. HMPV can cause upper and lower respiratory disease, and currently there is no vaccine to prevent it and no specific antiviral therapy to treat it, according to the Centers for Disease Control

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How TRICARE can help you screen for cancer

March 6, 2026 / Patient education / InnovateMed Author / cancer

FALLS CHURCH, Va. – Did you know that it’s possible to detect some types of cancer before you show any signs or symptoms? Getting preventive screening tests makes this possible.“Screening tests are a powerful tool for taking care of your health — If you have cancer, finding it early can help make it easier to treat,” said

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Measles is not the only disease on the rise. Mumps also may be making a comeback

March 6, 2026 / Patient education / InnovateMed Author / measles

By Katia Hetter Updated 5 hr ago Mumps is a viral infection caused by the mumps virus. It primarily affects the salivary glands. Cavallini James/BSIP/Universal Images Group/Getty Images Measles is not the only vaccine-preventable disease making headlines. Health officials in Maryland have issued an alert after confirming an uptick in mumps cases — 26 reported so

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