January 2026

Researchers pioneer contactless health monitoring

by Emma Frankham, University of Wisconsin-Madison edited by Lisa Lock, reviewed by Andrew Zinin  Editors’ notes  The GIST Add as preferred source Traditional clinical monitors being adjusted on a young patient. Credit: UW Health. When you think about monitoring heart and breathing rates, you likely picture a wearable device—a wristband, chest strap, or sticky patch connected to a […]

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People who survive cancers are less likely to develop Alzheimer’s. This might be why

by Justin Stebbing, The Conversation edited by Gaby Clark, reviewed by Andrew Zinin  Editors’ notes  The GIST Add as preferred source Credit: CC0 Public Domain Cancer and Alzheimer’s disease are two of the most feared diagnoses in medicine, but they rarely strike the same person. For years, epidemiologists have noticed that people with cancer seem less likely to

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Blood biomarker points to increased risk of brain metastasis in patients with inflammatory breast cancer

by University of Texas MD Anderson Cancer Center edited by Sadie Harley, reviewed by Andrew Zinin  Editors’ notes  The GIST Add as preferred source Credit: CC0 Public Domain Researchers at The University of Texas MD Anderson Cancer Center have identified a targetable driver of brain metastases in patients with aggressive inflammatory breast cancer. The study uncovers a novel

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Single-dose base editing corrects PKD1 mutation and extends survival in ADPKD preclinical models

by Kelley Luckstein, Mayo Clinic edited by Gaby Clark, reviewed by Andrew Zinin  Editors’ notes  The GIST Add as preferred source A single injection of Cbh-ABE9-dual-AAV9 decreases heart hypertrophy in Pkd1RC/RC mice. Credit: Nature Communications (2025). DOI: 10.1038/s41467-025-65997-1 Mayo Clinic researchers have developed a promising gene-editing therapy that directly corrects a genetic mutation responsible for autosomal dominant polycystic kidney disease (ADPKD), the

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Experimental immunotherapy clears harmful artery cells, reducing plaque in mice

by Washington University in St. Louis edited by Sadie Harley, reviewed by Robert Egan  Editors’ notes  The GIST Add as preferred source An immunotherapy reduces plaque in the arteries of mice, offering a potential new strategy to treat cardiovascular disease, according to a study led by WashU Medicine researchers. An artery from an untreated mouse (top) shows more

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Simple dietary change may slow liver cancer in at-risk patients

by Andrew Smith, Rutgers University edited by Stephanie Baum, reviewed by Robert Egan  Editors’ notes  The GIST Add as preferred source Credit: Pixabay/CC0 Public Domain People with compromised liver function may be able to reduce their risk of liver cancer or slow its progression with a simple dietary change: eating less protein. A Rutgers-led study in Science Advances has found that low-protein

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Taking daily aspirin does not reduce long-term cancer risk for older adults

by Monash University edited by Gaby Clark, reviewed by Robert Egan  Editors’ notes  The GIST Add as preferred source Credit: Pixabay/CC0 Public Domain Prior studies, largely among middle-aged adults, have reported that taking aspirin reduces the risk of cancer after 10 years, particularly for colorectal cancer. However, new Monash University research has found that for healthy older adults

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Metformin shown to prevent long COVID across risk groups in multiple randomized trials

by University of Minnesota Medical School edited by Stephanie Baum, reviewed by Andrew Zinin  Editors’ notes  The GIST Add as preferred source Credit: CC0 Public Domain Multiple randomized clinical trials and electronic health record studies now show that metformin, a widely used and well-established medication, significantly reduces the risk of developing long COVID when taken during or shortly

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Beyond the active site: A new way to regulate immune enzyme TREX1

by National Taiwan University edited by Gaby Clark, reviewed by Robert Egan  Editors’ notes  The GIST Add as preferred source Graphical Abstract. Credit: Nucleic Acids Research (2025). DOI:10.1093/nar/gkaf1511 The immune system must maintain a delicate balance to defend against harmful threats while avoiding excessive inflammation. When this balance is disrupted, immune responses can contribute to autoimmune diseases and cancer. A

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Discovery shines light on a cascade of events that occurs when toxic tau impacts synapses

by Buck Institute for Research on Aging edited by Sadie Harley, reviewed by Andrew Zinin  Editors’ notes  The GIST Add as preferred source Electron microscopy images of human neuron synapses 7 or 14 days after a 30-minute exposure to tau oligomers or vehicle control. In vehicle-treated neurons synaptic vesicles (red circles) are clustered near the active zone

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