Long-term use of tofersen slows ALS disease progression in people with a genetic subtype, provides hope for treating other forms of ALS by Julia Evangelou Strait•December 22, 2025 Huy Mach Rickey Malloy (left), who receives tofersen treatment for SOD1-ALS at WashU Medicine, plays a round of golf with his wife, Jenny, and their son, Kash. Long-term […]
New ALS drug stabilizes decline with a trend toward impro Read More »
“This study outlines shifting priorities and translational gaps in aging research and offers a scalable, data-driven alternative to conventional reviews.” Peer-Reviewed Publication Impact Journals LLC image: Figure 6. Mapping underexplored connections in the aging research literature through semantic overlap analysis. (A) Heatmap of average TF-IDF score of the top 20 most significant words from each cluster when
AI tracks nearly 100 years of aging research, revealing key trends and gaps Read More »
OpenAI has officially acknowledged a worrying reality: their Atlas AI browser, like all AI-powered browsers, will never be completely safe from prompt injection attacks. Most likely. Example of how a prompt injection attack text could look like. Image credit: OpenAI Key Takeaways: Prompt injection attacks against AI browsers cannot be fully eliminated, only managed through continuous defense
by Mass General Brigham edited by Gaby Clark, reviewed by Robert Egan Editors’ notes LOOCV Methods Schematic. Credit: Proceedings of the National Academy of Sciences (2025). DOI: 10.1073/pnas.2518159122 After traumatic brain injury (TBI), some patients may recover completely, while others retain severe disabilities. Accurately evaluating prognosis is challenging in patients on life-sustaining therapy. Though resting-state functional MRI (rs-fMRI) can assess neurological activity
Signature neural patterns may help predict recovery from traumatic brain injury Read More »
By Pooja Toshniwal PahariaReviewed by Benedette Cuffari, M.Sc. Introduction Top ACN-rich foods Mechanisms of action Benefits for brain health Cardiovascular effects Skin health benefits Optimal intake and safety References Further reading Purple foods aren’t just pretty! Here’s what anthocyanins are actually doing inside your body, and why the best evidence points to specific heart and brain benefits
Purple Power: Evidence-Based Health Benefits of Anthocyanin-Rich Diets Read More »
Frontiers JournalsDec 23 2025 A team led by clinicians and engineers has wrapped the plant-derived polyphenol pterostilbene (PSB) into prebiotic alginate/resistant-starch microcapsules coated with chitosan and shown that oral administration dampens dextran-sulfate-sodium (DSS) colitis in mice. The work, released online in Engineering, demonstrates that the 200-μm spheres escape gastric breakdown, accumulate in the colon for at
Interview conducted by Lauren HardakerDec 23 2025 Thought LeaderDr Bryony HendersonMedical Director for UK & USMedExpress In this interview, News Medical speaks with Dr Bryony Henderson, Medical Director for the UK and US at MedExpress, about the evolving role of GLP‑1 agonists in obesity care and the future of metabolic health treatments. Please introduce yourself and talk a little about
How GLP‑1 Agonists Are Shaping the Future of Obesity Treatment With Dr Bryony Henderson Read More »
Peer-Reviewed Publication KeAi Communications Co., Ltd. image: Engineered Stem Cell Vesicles for Real-Time Stroke Imaging and Therapy view more Credit: Xu Duan et al Ischemic stroke remains a leading global cause of disability and mortality, and a major challenge in stroke treatment is “reperfusion injury”—where return of blood flow causes oxidative stress and inflammation, further damaging
by University of Eastern Finland edited by Lisa Lock, reviewed by Robert Egan Editors’ notes Gln metabolism remodels macrophage functions and atherosclerotic lesions. Credit: Nature Metabolism (2025). DOI: 10.1038/s42255-025-01354-2 Two complementary studies reveal how an insufficient supply of energy in macrophages, key immune cells in artery walls, drives the progression of atherosclerosis—and how this knowledge could lead to better diagnostics
Immune cell ‘fuel’ shortages shape atherosclerosis, scientists reveal Read More »
by University of Vermont edited by Sadie Harley, reviewed by Robert Egan Editors’ notes The microvasculature of a brain imaged using two-photon laser scanning microscopy. Credit: Asser Bedair, Ph.D., Larner College of Medicine A possible new treatment for impaired brain blood flow and related dementias is on the horizon. Research by scientists at the University of Vermont Robert
Key phospholipid points to potential treatment for vascular dementia Read More »
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