December 3, 2025

Semaglutide and early-stage metabolic abnormalities in individuals with schizophrenia spectrum disorders

About The Study: The results of this randomized clinical trial show that adjunctive semaglutide significantly improved glycemic control and weight outcomes in individuals with schizophrenia spectrum disorders. Secondary outcomes were exploratory. These findings support the use of glucagon-like peptide–1 receptor agonists (GLP-1RAs) as a potential early intervention strategy to reduce cardiometabolic risk in this vulnerable population. […]

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Why undisturbed sleep is important to brain injury recovery

by Emily Caldwell, The Ohio State University edited by Stephanie Baum, reviewed by Robert Egan  Editors’ notes Experimental design and setup. (A) 8–10-week-old C57BL/6 received a sham injury or LFPI (Sham; TBI, N = 5–6) using a model of lateral fluid percussion injury (LFPI). Sham animals receive a 3-mm craniectomy but no fluid pulse. (B) Righting reflex time following LFPI

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Noninvasive approach to treating stroke by boosting the brain’s lymphatic system

by Kate Carthew, Monash University edited by Lisa Lock, reviewed by Andrew Zinin  Editors’ notes Credit: MART PRODUCTION from Pexels Scientists from Monash University are partnering with colleagues at the Yale School of Medicine in New Haven, Conn., to develop a new, high-tech approach for treating ischemic stroke by enhancing removal of toxic waste products from the brain.

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Sugar starts corroding your teeth within seconds. Here’s how to protect your pearly whites from decay

by José Lemos, Jacqueline Abranches, The Conversation edited by Lisa Lock, reviewed by Andrew Zinin  Editors’ notes Credit: CC0 Public Domain Between Halloween candy, Thanksgiving pies and holiday cookies, the end of the year is often packed with opportunities to consume sugar. But what happens in your mouth during those first minutes and hours after eating those sweets?

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Nearly one in five child deaths linked to growth failure, global analysis find

by Institute for Health Metrics and Evaluation edited by Lisa Lock, reviewed by Robert Egan  Editors’ notes Credit: Pixabay/CC0 Public Domain Nearly 1 million children around the globe fail to reach their fifth birthday every year due to devastating health consequences linked to child growth failure, making it the third leading risk factor for mortality and morbidity in

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What does it mean if I get flu after the jab? Do COVID boosters increase the risk of side-effects?

by Catherine Wilson, The Conversation edited by Gaby Clark, reviewed by Andrew Zinin  Editors’ notes Credit: Unsplash/CC0 Public Domain The flu season has started early this year, and we are prepared for it to be a bad one. Whether you have already had a vaccine or are thinking about getting one, here are some answers to questions you

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Ultrasound pinpoints vascular complications from cosmetic fillers

by Radiological Society of North America edited by Sadie Harley, reviewed by Andrew Zinin  Editors’ notes Vascular occlusion—the disruption of blood flow in arteries—on ultrasound from hyaluronic acid fillers. This ultrasound image shows absent blood flow in a segment of an artery of the lip. Credit: Rosa Maria Silveira Sigrist, M.D., and RSNA Ultrasound can aid in treating

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Rectal bleeding: Is it hemorrhoids or cancer?

by Richard Wender and Michael Sapienza edited by Sadie Harley, reviewed by Andrew Zinin  Editors’ notes Hemorrhoids are a common condition that affects about half of all people by age fifty. Although hemorrhoids are usually harmless, some worry that they may be a sign of cancer. While certain symptoms of hemorrhoids, colorectal cancer, and anal cancer do

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How the brain protects itself from Alzheimer’s disease

by Isabella Backman, Yale University edited by Lisa Lock, reviewed by Andrew Zinin  Editors’ notes Representative confocal images of LIII dlPFC of an aged macaque (28 years) labeled with GLO1 (green) and (A) excitatory neuronal markers MAP2 (magenta) and NeuN (blue), (B) astrocytic marker GFAP (magenta) and nuclei marker (blue), and (C) microglial marker IBA1 (magenta) and nuclei

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Vitamin C from food boosts collagen levels in skin

by University of Otago edited by Lisa Lock, reviewed by Andrew Zinin  Editors’ notes Credit: CC0 Public Domain A new study from researchers at the University of Otago, Faculty of Medicine—Christchurch Ōtautahi, has found that collagen production and skin renewal directly respond to the amount of vitamin C we eat. The study, published in the Journal of Investigative Dermatology, shows that

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