November 14, 2025

Researchers reveal intricate control system for key immune gene

November 14, 2025 / Research update / InnovateMed Author / immune gene

by Sarah C.P. Williams, Gladstone Institutes edited by Stephanie Baum, reviewed by Robert Egan Editors’ notes Credit: Immunity (2025). DOI: 10.1016/j.immuni.2025.10.020 The immune system faces a delicate balancing act: It must be aggressive enough to fight infections and cancer, yet restrained enough to avoid attacking the body’s own tissues. More than two decades ago, researchers identified a gene called FOXP3 […]

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FDA approves Caplyta for major depressive disorder in adults

November 14, 2025 / Clinical Practice / InnovateMed Author / major depressive disorder

by Lori Solomon edited by Stephanie Baum, reviewed by Robert Egan Editors’ notes The U.S. Food and Drug Administration has approved Caplyta (lumateperone) as an adjunctive therapy with antidepressants for the treatment of major depressive disorder in adults. This approval marks the fourth indication for Caplyta, the first and only FDA-approved treatment for bipolar I and II

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FDA approves Darzalex Faspro for high-risk smoldering multiple myeloma

November 14, 2025 / Clinical Practice / InnovateMed Author / multiple myeloma

by Lori Solomon edited by Stephanie Baum, reviewed by Robert Egan Editors’ notes The U.S. Food and Drug Administration has approved Darzalex Faspro (daratumumab and hyaluronidase-fihj) as a single-agent treatment for adult patients with high-risk smoldering multiple myeloma (HR-SMM). Darzalex Faspro is now the first and only approved treatment for HR-SMM. The approval is based on results

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Revised clinical practice guideline for treatment of chronic hypoparathyroidism in adults released

November 14, 2025 / Clinical Practice / InnovateMed Author / Chronic Hypoparathyroidism

by European Society of Endocrinology edited by Gaby Clark, reviewed by Andrew Zinin Editors’ notes Credit: Pixabay/CC0 Public Domain The European Society of Endocrinology (ESE) has published a Revised Clinical Practice Guideline for the Treatment of Chronic Hypoparathyroidism in Adults in the European Journal of Endocrinology. The Revised Guideline has been developed by an expert multidisciplinary panel chaired

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Monoclonal antibodies effectively prevent respiratory syncytial virus in infants

November 14, 2025 / Clinical Practice / InnovateMed Author / monoclonal antibodies

by European Centre for Disease Prevention and Control (ECDC) edited by Stephanie Baum, reviewed by Andrew Zinin Editors’ notes Credit: Unsplash/CC0 Public Domain Respiratory syncytial virus (RSV) is a common respiratory virus which usually causes mild, cold-like symptoms during the respiratory virus season. However, especially among young infants under six months of age or people over 65,

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Changes in a single gene can cause mental illness, study reveals

November 14, 2025 / Research update / InnovateMed Author / mental health

by Anne Grimm, Leipzig University edited by Sadie Harley, reviewed by Robert Egan Editors’ notes Credit: Pixabay/CC0 Public Domain Until now, researchers assumed that schizophrenia, anxiety disorders or depression arise from an interplay of many different factors, including genetic ones. An international study led by the Institute of Human Genetics at the University of Leipzig Medical Center has

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Unusual days signal rising migraine risk

November 14, 2025 / Research update / InnovateMed Author / migraine

by Justin Jackson, Medical Xpress edited by Sadie Harley, reviewed by Robert Egan Editors’ notes Credit: Unsplash/CC0 Public Domain Harvard Medical School researchers report that higher day-to-day “trigger surprisal” scores were associated with migraine attacks over the next 12 and 24 hours. In this cohort, higher surprisal scores aligned with greater odds of a headache attack, even after

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Speeding the detection of three serious regional fungal infections

November 14, 2025 / Research update / InnovateMed Author / fungal infection

by Association for Molecular Pathology edited by Sadie Harley, reviewed by Robert Egan Editors’ notes Credit: CC0 Public Domain Certain serious fungal infections occur in regions of the United States with specific environments and are often tied to soil exposure. These infections can affect both healthy and immunocompromised people, but proper diagnosis remains slow, which delays treatment.

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AI crime wave

November 14, 2025 / News update / InnovateMed Author / crime wave

Illustration: Sarah Grillo/Axios AI is rewriting the playbook for crime — from cheap deepfake scams and AI-written ransomware to mass identity hijacks and critical-infrastructure hacks, Axios’ Russell Contreras writes. Why it matters: This new class of AI-supercharged crime is endangering lives and financial systems. Police training, laws and cross-border tools aren’t keeping up. Off-the-shelf AI lowers the skill

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Magnetic nanoparticles that successfully navigate complex blood vessels may be ready for clinical trials

November 14, 2025 / Research update / InnovateMed Author / magnetic nanoparticles

by ETH Zurich edited by Sadie Harley, reviewed by Robert Egan Editors’ notes The latest ETH micro robot is this small. Credit: Luca Donati / lad.studio Zurich Every year, 12 million people worldwide suffer a stroke; many die or are permanently impaired. Currently, drugs are administered to dissolve the thrombus that blocks the blood vessel. These drugs spread throughout the

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