September 2025

FDA approves Opzelura for atopic dermatitis in children

by Lori Solomon edited by Stephanie Baum, reviewed by Robert Egan  Editors’ notes The U.S. Food and Drug Administration has approved Opzelura cream 1.5% (ruxolitinib) for children ages 2 to 11 years with atopic dermatitis (AD). The approval is the first topical Janus kinase (JAK) inhibitor for the short-term, noncontinuous chronic treatment of mild-to-moderate AD in nonimmunocompromised […]

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Biologic drug reduces symptoms and hospitalization for severe pulmonary hypertension after diagnosis in clinical trial

by University of Michigan edited by Stephanie Baum, reviewed by Robert Egan  Editors’ notes Credit: Unsplash/CC0 Public Domain Prescribing the biologic drug sotatercept alongside standard treatment for the most severe form of pulmonary hypertension significantly reduces the likelihood of worsening disease when added within the first year after diagnosis, according to a study published in the New England Journal

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Q&A: Is the medical community on the brink of a cure for Huntington’s disease?

by Jane Kelly, University of Virginia edited by Lisa Lock, reviewed by Andrew Zinin  Editors’ notes Credit: John DiJulio, University Communications Huntington’s disease is a fatal, hereditary neurological disorder mostly striking people between the ages of 30 and 50. In 1872, a young physician, Dr. George Huntington, first described the disease in detail. Since then, a cure has

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Altering one area of the brain could rid alcohol withdrawal symptoms, study finds

by Devin Rokyta, Washington State University edited by Gaby Clark, reviewed by Andrew Zinin  Editors’ notes Graphical abstract. Credit: Neuropharmacology (2025). DOI: 10.1016/j.neuropharm.2025.110595 By targeting a specific area of the brain, researchers at Washington State University may now hold the key to curbing the debilitating symptoms of alcohol withdrawal that push many people back to drinking. The new study found

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Fat particles could be key to treating metabolic brain disorders

by University of Queensland edited by Lisa Lock, reviewed by Robert Egan  Editors’ notes Hippocampal neurons (magenta), labelled for DDHD2 (cyan) and endomembranes (yellow). Credit: University of Queensland Evidence challenging the long-held assumption that neuronal function in the brain is solely powered by sugars has given researchers new hope of treating debilitating brain disorders. A University of Queensland

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Exercise can help to restore the immune system of people with post-COVID syndrome

by European Respiratory Society edited by Stephanie Baum, reviewed by Andrew Zinin  Editors’ notes Credit: CC0 Public Domain Exercise can help to restore a more normal, well-regulated immune system in people with post-COVID syndrome, according to a gold-standard randomized-controlled trial presented at the European Respiratory Society Congress in Amsterdam, the Netherlands. The study was presented by Dr. Enya Daynes,

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Advanced AI tool detects tiny brain lesions in children with epilepsy

by Murdoch Children’s Research Institute edited by Sadie Harley, reviewed by Robert Egan  Editors’ notes Credit: Unsplash/CC0 Public Domain An advanced AI tool can detect tiny brain lesions that cause severe epilepsy in children, allowing faster diagnosis, more precise treatment and a potential cure, according to a new study. Developed by a team at Murdoch Children’s Research Institute

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Residential sulfur dioxide exposure linked to higher odds of amyotrophic lateral sclerosis onset

by Justin Jackson, Phys.org edited by Sadie Harley, reviewed by Robert Egan  Editors’ notes Credit: CC0 Public Domain Université de Sherbrooke and Canadian collaborators report an association between long-term residential sulfur dioxide exposure and higher odds of amyotrophic lateral sclerosis (ALS) onset. ALS is a rare motor neuron disease with limited therapeutic options and substantial mortality within a

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Obesity genes tied to kidney, eye and nerve damage in diabetes

by Association of Basic Medical Sciences of FBIH edited by Gaby Clark, reviewed by Robert Egan  Editors’ notes Credit: Biomolecules and Biomedicine (2025). DOI: 10.17305/bb.2025.11897 A large genome-wide analysis reports that common obesity traits share, and in some cases drive, risk for diabetic kidney disease, diabetic retinopathy, and diabetic neuropathy. The study maps shared DNA signals, tests causal links, and

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Cannabis extract shown to ease chronic lower back pain in high-quality clinical trial

by Daniel Lawler edited by Andrew Zinin  Editors’ notes While the trial suggests something in the cannabis plant can treat pain, that does not mean all marijuana has the same effect, researchers say. A specially developed cannabis extract relieves chronic lower back pain, according to a clinical trial published Wednesday that experts are calling the first

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