September 2025

Nonpharmacologic Approaches Show Promise in GERD Treatment –

September 30, 2025 / Research update / InnovateMed Author / GERD treatment

TOPLINE: Compared with conventional Western medicine, nonpharmacologic therapies, either alone or combined with other treatments, more effectively increased lower esophageal sphincter pressure and reduced esophageal acid exposure time in patients with gastroesophageal reflux disease (GERD). METHODOLOGY: Researchers conducted a network meta-analysis to evaluate the efficacy and safety of nonpharmacologic interventions, either alone or in combination with pharmacologic […]

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Show Not Tell: Stool Photos Transform GI Visits

September 30, 2025 / Clinical Practice / InnovateMed Author / stool

What’s your response when a patient says, “I took a picture of my stool. Do you want to see it?” Do you glance at it quickly? Do you ask clarifying questions? Or do you quickly mumble something and divert your gaze?” Hi, I’m Alicia Muratore, a gastroenterologist at the University of North Carolina, and this

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Train your brain

September 30, 2025 / News update / InnovateMed Author / brain

Illustration: Aïda Amer/Axios You’ve probably seen the promise on social media: Just “manifest” your way to a better life. Now, more doctors and educators agree that there may be tangible benefits to training your brain to focus on a meaningful intention, Axios’ Ashley May writes. 💡 The intrigue: The late James Doty, a neurosurgeon and professor at Stanford

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Europe: B-Cell Therapy Moves Into IgG4-Related Disease

September 30, 2025 / Clinical Practice / InnovateMed Author / B cell therapy

The European Medicines Agency’s (EMA) Committee for Medicinal Products for Human Use (CHMP) has recommended expanding the therapeutic indication of Uplizna (inebilizumab, Amgen Europe) to include treatment of adult patients with active immunoglobulin G4-related disease (IgG4-RD). The decision marks the first authorized medicine in the EU for this rare autoimmune condition. Uplizna is already authorized in the

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Diagnostic Accuracy of Nasal Allergy Test in Allergic Rhinitis

September 30, 2025 / Research update / InnovateMed Author / allergic rhinitis

TOPLINE: A nasal allergy test showed strong diagnostic performance, with sensitivity exceeding 75% and specificity approaching 90% for detecting allergens sensitized in patients with allergic rhinitis. METHODOLOGY: Researchers conducted a prospective study between 2010 and 2012 to evaluate the diagnostic performance of a nasal allergy test that directly detects allergen-specific immunoglobulin E (IgE) in the nasal

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What the World’s Oldest Woman Teaches Us About Longevity

September 30, 2025 / Research update / InnovateMed Author / longevity

Scientists decoded the biology of a 117-year-old woman. The results challenge what we think aging markers can and can’t tell us about living longer. Maria Branyas Morera lived a long, full life. Born in San Francisco in 1907, she played piano into her 110s, gardened, stayed close with family and friends, she followed a

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Older Adults More Likely to Have Severe Anaphylaxis, Less Likely to Receive Epinephrine

September 30, 2025 / Clinical Practice / InnovateMed Author / anaphylaxis

Whitney McKnight September 26, 2025 Older adults are at greater risk for severe anaphylaxis in a variety of settings but are less likely to receive epinephrine than younger adults, two recent studies have found. In the first study, published last month in JACI in Practice, investigators determined that older adults had increased odds of reactions to medications and intravenous (IV) contrast

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GLP-1s for Sleep Apnea: What They Can (and Can’t) Do

September 30, 2025 / Clinical Practice / InnovateMed Author / apnea

Hi. I’m Dr Alison Kole, a triple-boarded pulmonary, critical care, and sleep medicine physician and the creator and host of the Sleep Is My Waking Passion podcast. Today I want to speak to you about a critical intersection in medicine, which is obesity and obstructive sleep apnea (aka OSA) and why this topic is especially relevant for those of us in

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Don’t Miss These Clues in Interstitial Lung Disease

September 30, 2025 / Clinical Practice / InnovateMed Author / lung disease

This transcript has been edited for clarity. Hi, everyone. Dr Chandrasekaran here. Today, I’m going to talk about interstitial lung disease. This is a common diagnosis that we as pulmonologists see, whether it’s inpatient or outpatient, as this is associated with many various conditions. When we do see these patients, our first clue into their

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Can Lung Ultrasound Cut Antibiotic Prescriptions in General

September 30, 2025 / Clinical Practice / InnovateMed Author / lung ultrasound

TOPLINE: Focused lung ultrasound did not achieve the anticipated reduction in antibiotic prescriptions during initial consultations in general practice among adults with acute cough and symptoms of lower respiratory tract infection compared with usual care. However, it significantly decreased reconsultations for lower respiratory tract infections. METHODOLOGY: A pragmatic randomized superiority trial was conducted in Denmark

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