September 25, 2025

Childhood concussions may trigger long-term brain changes

by Iqbal Pittalwala, University of California – Riverside edited by Gaby Clark, reviewed by Andrew Zinin  Editors’ notes Andre Obenaus is a a professor of biomedical sciences at UC Riverside’s School of Medicine. Credit: Stan Lim, UC Riverside. A new study in mice reports that concussions sustained early in life can cause subtle brain changes that re-emerge later […]

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New protein interaction map sheds light on how brain cell communication breaks down in Alzheimer’s disease

by The Mount Sinai Hospital edited by Sadie Harley, reviewed by Robert Egan  Editors’ notes Credit: Pixabay/CC0 Public Domain A new study led by the Icahn School of Medicine at Mount Sinai offers one of the most comprehensive views yet of how brain cells interact in Alzheimer’s disease, mapping protein networks that reveal communication failures and point to

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While it may go unnoticed, loss of smell may linger for years after COVID-19

by NYU Langone Health edited by Robert Egan  Editors’ notes Credit: Pixabay/CC0 Public Domain People who suspect that their sense of smell has been dulled after a bout of COVID-19 are likely correct, a new study using an objective, 40-odor test shows. Even those who do not notice any olfactory issues may be impaired. Led by the

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Can a mango a day keep diabetes away?

by George Mason University edited by Sadie Harley, reviewed by Andrew Zinin  Editors’ notes Credit: Unsplash/CC0 Public Domain If presented with two snacks, one containing 7 grams of sugar and another with over 30 grams of sugar, choosing the healthier option should be a no-brainer, correct? Well, maybe not. Less sugar is not automatically healthier. For the nearly

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Adding a lookup step makes AI better at assigning medical diagnosis codes

by The Mount Sinai Hospital edited by Stephanie Baum, reviewed by Robert Egan  Editors’ notes Credit: Pixabay/CC0 Public Domain A new study by researchers at the Mount Sinai Health System suggests that a simple tweak to how artificial intelligence (AI) assigns diagnostic codes could significantly improve accuracy, even outperforming physicians. The findings, reported in NEJM AI, could help reduce

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CU Anschutz researchers discover how lymphatic endothelials cells help the body remember infections

The discovery could help pave the way for next-generation vaccines and immune therapies Peer-Reviewed Publication University of Colorado Anschutz Medical Campus A study published today in Nature Communications describes how lymphatic endothelial cells assist in generating robust immune memory, offering new insights into how the immune system functions. Specifically, the researchers found there is a particular genetic

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UPF researchers design a new experimental screening system to identify peptides with therapeutic potential

The research has been carried out in conjunction with Stanford University and has enabled designing a screening system to identify extremely selective peptides with therapeutic potential that minimize the unwanted side effects so often found with commercial Peer-Reviewed Publication Universitat Pompeu Fabra – Barcelona Juan Herrero Bourdieu-Puyade & Marta Barniol Xicota. view moreCredit: Pompeu Fabra

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Exploring the therapeutic potential of TGF-β inhibitors for liver fibrosis: targeting multiple signaling pathways

Peer-Reviewed Publication Xia & He Publishing Inc. image: Schematic representation of different strategies targeting TGF-β signaling for liver fibrosis therapy. TGF-β signaling inhibitors hold important therapeutic potential for hepatic fibrosis. Although many challenges remain, detailed exploration of these inhibitors, including certain natural products, is necessary to clarify their anti-fibrotic effects. In the future, effective anti-fibrotic

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DA guidance may speed gene therapy approvals

  By Maya Goldman Photo: Sarah Silbiger/Getty Images The FDA said yesterday it will allow innovative clinical trials to help streamline reviews of cell and gene therapies for rare diseases that affect small numbers of patients. Why it matters: The guidance shows the agency’s interest in using accelerated pathways for regenerative therapies, similar to what’s in place for

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Gut microbiota and immune response linked to breast cancer risk

by Association of Basic Medical Sciences of FBIH edited by Gaby Clark, reviewed by Robert Egan  Editors’ notes Credit: Unsplash/CC0 Public Domain Breast cancer remains one of the most common cancers worldwide and a leading cause of cancer-related deaths among women. Despite advances in screening and treatment, advanced stages of the disease remain difficult to manage, and researchers

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