September 9, 2025

New AI tool pinpoints genes, drug combos to restore health in diseased cells

September 9, 2025 / Research update / InnovateMed Author / diseased cells

New model could optimize drug discovery Peer-Reviewed Publication Harvard Medical School In a move that could reshape drug discovery, researchers at Harvard Medical School have designed an artificial intelligence model capable of identifying treatments that reverse disease states in cells. Unlike traditional approaches that typically test one protein target or drug at a time in […]

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Mapping causality in neuronal activity: towards a better understanding of brain networks

September 9, 2025 / Research update / InnovateMed Author / brain network

Researchers develop a method to identify connections between neurons solely based on spike train data Peer-Reviewed Publication Tokyo University of Science image: A new method of CCM using which connections between neurons can be inferred based on the causal relationships between spike train data. view moreCredit: Dr. Kazuya Sawada from Tokyo University of Science, Japan

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High consumption of ultra-processed foods linked to systemic inflammation

September 9, 2025 / Clinical Practice / InnovateMed Author / systemic inflammation

Peer-Reviewed Publication Florida Atlantic University image: Participants consumed a median of 35% of their daily calories from UPFs, ranging from just 0% to 19% in the lowest group to 60% to 79% in the highest. view moreCredit: Alex Dolce, Florida Atlantic University Ultra-processed foods (UPFs) are industrially altered products – like soda, snacks and processed

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Brain iron on MRI predicts cognitive impairment, decline

September 9, 2025 / Research update / InnovateMed Author / brain iron, MRI

Peer-Reviewed Publication Radiological Society of North America A special MRI technique that detects iron levels in different regions of the brain can predict the onset of mild cognitive impairment and cognitive decline in cognitively unimpaired older adults, potentially creating a pathway to earlier interventions, according to a study published today in Radiology, a journal of the

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Stem cell models reveal how epilepsy genes disrupt different brain regions

September 9, 2025 / Research update / InnovateMed Author / stem cell model

by Tiare Dunlap, University of California, Los Angeles edited by Stephanie Baum, reviewed by Robert Egan Microscopy image of a human stem cell-derived hippocampal organoid. When the tissue carries an epilepsy-causing variant in the SCN8A gene, inhibitory neurons (seen in red) are disrupted, and hippocampal brainwave activity patterns are altered. Credit: Kevin Lozano, Ranmal Samarasinghe Lab For families

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GLP-1 weight-loss drugs pose hidden risks for young women, warn experts

September 9, 2025 / Clinical Practice / InnovateMed Author / GLP 1

by Flinders University edited by Sadie Harley, reviewed by Andrew Zinin Credit: Unsplash/CC0 Public Domain Women taking popular weight-loss medications during their reproductive years may be unaware of associated risks to pregnancy and unborn babies, warn Flinders University researchers. A new study has revealed that most Australian women of reproductive age prescribed GLP-1 receptor agonists—medications increasingly used

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Rethinking how our brains build the neural networks underlying motor memories

September 9, 2025 / Research update / InnovateMed Author / motor memories

by Nathan Collins, Stanford University edited by Stephanie Baum, reviewed by Robert Egan Credit: Pixabay/CC0 Public Domain For every motor skill you’ve ever learned, whether it’s walking or watchmaking, there is a small ensemble of neurons in your brain that makes that movement happen. Our brains trigger these ensembles—what we sometimes call “muscle memories”—to get our bodies

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Popular diabetes drug shows anti-aging effects among patients with type 2 diabetes

September 9, 2025 / Research update / InnovateMed Author / type 2 diabetes

by Sanjukta Mondal, Phys.org edited by Stephanie Baum, reviewed by Robert Egan Henagliflozin significantly increased telomere length compared to placebo. Credit: Cell Reports Medicine (2025). DOI: 10.1016/j.xcrm.2025.102331 Henagliflozin, a popular drug prescribed for type 2 diabetes, has demonstrated potential anti-aging effects in a recent study published in Cell Reports Medicine. Telomeres are protective caps made of repetitive DNA sequences that sit at

Specialized macrophages on adipose nerves curb age-related inflammation in mice

September 9, 2025 / Research update / InnovateMed Author / adipose nerves, macrophages

by Justin Jackson, Phys.org edited by Sadie Harley, reviewed by Robert Egan Schematic of experimental procedure for iv labeling of circulating cells with CD45.2 antibody (CD45.2iv) via retro-orbital delivery in 2-month-old and 22-month-old male and female mice. Credit: Nature Aging (2025). DOI: 10.1038/s43587-025-00952-9 Yale School of Medicine-led research reports that nerve-associated macrophages help maintain healthy fat over a lifespan

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Study of identical twins links faster aging to memory decline

September 9, 2025 / Research update / InnovateMed Author / memory decline

by Zeina Mohammed, University of Virginia edited by Lisa Lock, reviewed by Andrew Zinin UVA researchers are gleaning new information about biological markers of aging and cognitive decline from a longtime study on twins based in Kentucky. Credit: Tobias Wilbur, University Communications New research from University of Virginia psychologists has found that “epigenetic clocks”—tools scientists use to estimate

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