September 1, 2025

Stem cell research takes a step toward smart blood sugar control in diabetes

by Peking University edited by Sadie Harley, reviewed by Robert Egan   Credit: Cell Stem Cell (2025). DOI: 10.1016/j.stem.2025.07.006 Professor Deng Hongkui’s team from the Peking University School of Life Sciences has made the first successful differentiation of human pluripotent stem cells into fully endocrine-subtype-complete islets. These islets efficiently respond to blood glucose concentration changes, demonstrating very effective blood sugar […]

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Common inflammation drug may slow blood mutation, related cardiovascular disease risk

by American College of Cardiology edited by Gaby Clark, reviewed by Andrew Zinin   Central Illustration. Credit: JACC (2025). DOI: 10.1016/j.jacc.2025.07.058 Taking low-dose colchicine daily may slow the progression of a common acquired gene mutation found in the blood of older adults that can lead to certain blood cancers and increased risk of cardiovascular disease (CVD), according to a subanalysis

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Clinical trial shows constipation drug can treat patients with chronic kidney disease

by Tohoku University edited by Sadie Harley, reviewed by Robert Egan Administering lubiprostone alters gut microbiota, leading to improved mitochondrial function and suppression of inflammation. This improved renal function by increasing the levels of aguA and polyamines. Credit: Shun Watanabe Chronic kidney disease (CKD) is a major health issue worldwide. Many patients end up requiring regular dialysis to

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Leukemia stem cell-based method aids relapse prediction in acute myeloid leukemia

by Lori Solomon edited by Gaby Clark, reviewed by Andrew Zinin   An assay that uses leukemia stem cells (LSCs) to assess measurable residual disease (MRD) outperforms traditional methods in patients with acute myeloid leukemia (AML), according to a study published online Aug. 23 in Bone Marrow Transplantation. Si-Qi Li, from the Peking University People’s Hospital in Beijing, and colleagues

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Scientists solve medical mystery behind rare multi-organ disease, opening door to new treatments

by Duke-NUS Medical School edited by Sadie Harley, reviewed by Robert Egan Skin fibroblasts in a healthy individual (left) and skin fibroblasts with enlarged lysosomes and cholesterol build-up in in a patient with SPNS1 mutations (right). Credit: Duke-NUS Medical School A team of scientists led by Duke-NUS Medical School has solved a mystery behind a rare and previously

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Millions of women rely on contraceptives, but a new study shows they may do more than just prevent pregnancy

by Kat Cosley Trigg, Rice University edited by Robert Egan   Credit: Unsplash/CC0 Public Domain Hormonal birth control is a fact of life for millions of women. In the U.S. alone, more than 60 million women of reproductive age have used contraceptives according to the Centers for Disease Control and Prevention, most often to prevent pregnancy but

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Humble stethoscope gets an upgrade: AI helps it detect three heart conditions in 15 seconds

by British Heart Foundation edited by Sadie Harley, reviewed by Robert Egan   Credit: British Heart Foundation An AI-enabled stethoscope can help doctors pick up three heart conditions in just 15 seconds, according to the results of a real-world trial presented at the European Society of Cardiology’s annual congress in Madrid. The paper is also published in the journal BMJ Open. The

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Can vitamin D supplements really slow aging, as a recent study suggests?

by Dervla Kelly, The Conversation edited by Sadie Harley, reviewed by Andrew Zinin Credit: Unsplash/CC0 Public Domain Vitamin D supplements could help protect the caps on our chromosomes that slow aging, sparking hopes the sunshine vitamin might keep us healthier for longer, a recent study suggests. The researchers discovered that taking 2,000 IU (international units, a standard measure

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Drugs from China are reshaping biotech. Track the licensing deals here.

Biopharmaceutical firms in the U.S. and Europe are increasingly turning to China’s biotech sector for new medicines. Follow this year’s dealmaking with this database. Published Aug. 25, 2025 • By Ben Fidler A technician works in a Sinovac Biotech laboratory on September 24, 2020 in Beijing, China. Kevin Frayer via Getty Images The makeup of the

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RSV Vaccine Effectiveness Wanes Early in Older Adults – immunology

August 26, 2025  For older adults, the vaccine against respiratory syncytial virus (RSV) appears to be most effective in the first year after administration, according to new research that shows the benefits of the immunization fall roughly 60% within about 1.5 years. The database analysis showed that among adults aged 60 years or older, the effectiveness of the

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